180339-72-4

Basic information

• Product Name: 7-[(dimethylamino)methylene]-4,5,6,7-tetrahydro-4-(4-nitrobenzoyl)-8H-thieno [3,2-b]azepin-8-one
• Synonyms: 7-[(dimethylamino)methylene]-4,5,6,7-tetrahydro-4-(4-nitrobenzoyl)-8H-thieno [3,2-b]azepin-8-one
• CAS NO: 180339-72-4
• Molecular Weight: 371.417
• Mol File: 180339-72-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-[(dimethylamino)methylene]-4,5,6,7-tetrahydro-4-(4-nitrobenzoyl)-8H-thieno [3,2-b]azepin-8-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[(dimethylamino)methylene]-4,5,6,7-tetrahydro-4-(4-nitrobenzoyl)-8H-thieno [3,2-b]azepin-8-one(180339-72-4)
• EPA Substance Registry System: 7-[(dimethylamino)methylene]-4,5,6,7-tetrahydro-4-(4-nitrobenzoyl)-8H-thieno [3,2-b]azepin-8-one(180339-72-4)

Safety Data

• Hazardous Substances Data: 180339-72-4(Hazardous Substances Data)

Upstream product

• 180340-58-3 (4-nitrophenyl)(5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepin-4-yl)methanone 
• 94252-22-9 6,7-dihydro-5H-benzo[b]thiophene-4-one O-tosyloxime 
• 180340-57-2 5,6,7,8-tetra-hydro-4H-thieno[3,2-b]azepine 
• 4751-61-5 4,6,7,8-Tetrahydro-4H-thieno[3,2-b]azepin-5-one 
• 19995-19-8 4,5,6,7-tetrahydro-4-oxobenzo[b]thiophene oxime 
• 13414-95-4 4-keto-4,5,6,7-tetrahydrothianaphthene 
• 5815-08-7 tert-Butoxybis(dimethylamino)methane 
• 180340-59-4 4-(4-Nitrobenzoyl)-4,5,6,7-tetrahydro-8H-thieno[3,2-b]-azepin-8-one 

Downstream Products

• 180340-33-4 2,4,5,6-tetrahydro-2-methyl-6-(4-aminobenzoyl)pyrazolo[3,4-d]thieno[3,2-b]azepine 
• 276867-99-3 6-(4-aminobenzoyl)pyrazolo[3,4-d]thieno[3,2-b]azepine 

Relevant articles and documents

The synthesis and vasopressin (AVP) antagonist activity of a novel series of N-Aroyl-2,4,5,6-tetrahydropyrazolo-[3,4-d]thieno[3,2-b]azepines

Synthesis and SAR of N-[4-[(4,5-dihydropyrazolo[3,4-d]thieno[3,2-b]azepin-6(2H)-yl)carbonyl]phenyl]be nzamides as arginine vasopressin (AVP) receptor antagonists are discussed. Potent orally active AVP receptor antagonists are produced when the benzamide moiety contains a phenyl group at the 2-position. Similar analogues of 4,6,7,8-tetrahydro-5H-thieno[3,2-b]azepine and VPA-985 are reported. (C) 2000 Elsevier Science Ltd. All rights reserved.