19340-77-3

Basic information

• Product Name: N-BENZYL-2-HYDROXYACETAMIDE
• Synonyms: N-BENZYL-2-HYDROXYACETAMIDE
• CAS NO: 19340-77-3
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.19
• Mol File: 19340-77-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 398.1°Cat760mmHg
• Flash Point: 194.6°C
• Appearance: /
• Density: 1.161g/cm³
• Vapor Pressure: 4.73E-07mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: N-BENZYL-2-HYDROXYACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BENZYL-2-HYDROXYACETAMIDE(19340-77-3)
• EPA Substance Registry System: N-BENZYL-2-HYDROXYACETAMIDE(19340-77-3)

Safety Data

• Hazardous Substances Data: 19340-77-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H11NO2/c11-7-9(12)10-6-8-4-2-1-3-5-8/h1-5,11H,6-7H2,(H,10,12)

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Downstream Products

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Relevant articles and documents

CATALYST FOR CONVERTING ESTER TO AMIDE USING HYDROXYL GROUP AS ORIENTATION GROUP

Provided is a method for amidating a hydroxy ester compound at a high chemical selectivity. The amidation reaction method for a hydroxy ester compound comprises, in the presence of a catalyst containing a compound of a transition metal of the group 4 or group 5 in the periodic table, reacting at least one kind of hydroxy ester compound selected from the group consisting of an α-hydroxy ester compound, a β-hydroxy ester compound, a γ-hydroxy ester compound and a δ-hydroxy ester compound with an amino compound so as to amidate an ester group having a hydroxyl group at the α-, β-, γ- or δ-position of the hydroxy ester compound.

ADENOSINE RECEPTOR BINDING COMPOUNDS

The present invention relates to pharmaceutical compounds and compositions of Formula (I) and methods of treatment using the compounds and compositions, especially for the treatment and/or prevention of a proliferation disorder, such as cancer. Compounds of Formula (I) as further described herein are shown modulators of the adenosine A2A receptor and exhibit antiproliferative activity. Accordingly, these compounds are useful to treat proliferative disorders such as cancer, and other adenosine receptor-related conditions including an inflammatory disease, renal disease, diabetes, vascular disease, lung disease, or an autoimmune disease.

The use of 2-hydroxymethyl benzoic acid as an effective water surrogate in the Passerini reaction: A straightforward access to α-hydroxyamides

Dozens of strategies have been described for the synthesis of α-hydroxyamides over the years, but they share common drawbacks in terms of generality and tolerability, especially to acid labile functionalities. Here we report a truncated Passerini reaction suitable for the easy and mild preparation of functionalized α-hydroxyamides. In particular, this procedure is tolerant to acid sensitive protecting groups, which remain intact during the multicomponent reaction.