1949-78-6 Usage
Description
L-Lyxose, also known as ChEBI, is an L-lyxose in cyclic pyranose form. It is a white fine crystalline powder that acts as a reducing carbohydrate present in maple syrup. L-Lyxose is used in various applications due to its unique chemical properties and biological functions.
Uses
Used in Maple Syrup Industry:
L-Lyxose is used as a reducing carbohydrate in the maple syrup industry, contributing to the unique taste and properties of the syrup.
Used in Pharmaceutical Research:
L-Lyxose is used as a molecular modeling tool for studying drug binding and recognition in relation to aldose reductase. This application aids in the development of new drugs and understanding their mechanisms of action.
Used in Microbiology:
L-Lyxose is utilized by Escherichia coli, which encodes a kinase for L-Xylulose. This application highlights the role of L-Lyxose in microbial metabolism and its potential use in biotechnological processes.
Purification Methods
The anomer crystallises from propan-1-ol or EtOH, and the anomer crystallises from propan-2-ol. The 2,4-dinitrophenylhydrazone has m 171-172o and [] D -31o (pyridine). In D2O it has 21% of the pyranose form. The 2-methyl ether has m 120-121o and [] D +6o (c 1, H2O). [Angyal Adv Carbohydr Chem 42 15 1984, Bently J Am Chem Soc 79 1720 1959, Beilstein 1 I 439, 1 IV 4232.]
Check Digit Verification of cas no
The CAS Registry Mumber 1949-78-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,4 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1949-78:
(6*1)+(5*9)+(4*4)+(3*9)+(2*7)+(1*8)=116
116 % 10 = 6
So 1949-78-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4-,5-/m0/s1
1949-78-6Relevant articles and documents
Bentley
, p. 1720,1722,1725 (1957)
L-Ribose: An easily prepared rare sugar
Angyal, Stephen J.
, p. 58 - 59 (2005)
A method to synthesize L-ribose was described by molybdate-catalyzed epimerization of the readily available L-arabinose. The synthesis is one-step and except for a catalytic amount of molybdic acid do not require any expensive reagents, while the solvents used are water and a small amount of methanol. The process can be carried out in 2-3 days. Although the yield of L-ribose is only 20%, being in equilibrium with arabinose, most of the unreacted arabinose is recoverable and can be used again.
A heterogeneous Pd-Bi/C catalyst in the synthesis of l-lyxose and l-ribose from naturally occurring d-sugars
Fan, Ao,Jaenicke, Stephan,Chuah, Gaik-Khuan
supporting information; experimental part, p. 7720 - 7726 (2011/12/04)
A critical step in the synthesis of the rare sugars, l-lyxose and l-ribose, from the corresponding d-sugars is the oxidation to the lactone. Instead of conventional oxidizing agents like bromine or pyridinium dichromate, it was found that a heterogeneous catalyst, Pd-Bi/C, could be used for the direct oxidation with molecular oxygen. The composition of the catalyst was optimized and the best results were obtained with 5:1 atomic ratio of Pd:Bi. The overall yields of the five-step procedure to l-ribose and l-lyxose were 47% and 50%, respectively. The synthetic procedure is advantageous from the viewpoint of overall yield, reduced number of steps, and mild reaction conditions. Furthermore, the heterogeneous oxidation catalyst can be easily separated from the reaction mixture and reused with no loss of activity.