23164-60-5Relevant articles and documents
Green aqueous synthesis and antimicrobial evaluation of 3,5-disubstituted 1,2,4-triazoles
Beyzaei, Hamid,Malekraisi, Farideh,Aryan, Reza,Ghasemi, Behzad
, p. 482 - 487 (2020/05/25)
[Figure not available: see fulltext.] An eco-friendly and simple procedure was proposed for the synthesis of 3,5-disubstituted 1,2,4-triazoles by optimized reaction of benzamidine hydrochloride and various aryl hydrazides. H2O and K2
Heterogeneous Copper(I)-Catalyzed Cascade Addition-Oxidative Cyclization of Nitriles with 2-Aminopyridines or Amidines: Efficient and Practical Synthesis of 1,2,4-Triazoles
Xia, Jianhui,Huang, Xue,Cai, Mingzhong
, p. 2014 - 2022 (2019/04/26)
The heterogeneous cascade addition-oxidative cyclization of nitriles with 2-aminopyridines or amidines was achieved in 1,2-dichlorobenzene or DMSO at 120-130 °C by using a 1,10-phenanthroline-functionalized MCM-41-supported copper(I) complex [Phen-MCM-41-
An efficient and recyclable heterogeneous catalytic system for the synthesis of 1,2,4-triazoles using air as the oxidant
Meng, Xu,Yu, Chaoying,Zhao, Peiqing
, p. 8612 - 8616 (2014/03/21)
Copper-zinc supported on Al2O3-TiO2 was found as a simple and efficient heterogeneous catalyst for the oxidative synthesis of 1,2,4-triazole derivatives using air as the green oxidant under ligand-, base- and additive-free conditions. The heterogeneous reactions carried out smoothly with a large range of substrates, including NO2-, vinyl-, pyrimidine- and imidazole-contained starting materials, and provided corresponding triazoles in moderate to excellent yields with low catalyst loading (1.6 mol%). Furthermore, the catalyst can be simply recycled many times without significant loss in catalytic activity. The Royal Society of Chemistry.