24318-00-1

Basic information

• Product Name: 1-(BENZYLOXY)-3-NITROBENZENE
• Synonyms: 1-(BENZYLOXY)-3-NITROBENZENE;3-(Benzyloxy)nitrobenzene
• CAS NO: 24318-00-1
• Molecular Formula: C₁₃H₁₁NO₃
• Molecular Weight: 229.23134
• Mol File: 24318-00-1.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 378.8°Cat760mmHg
• Flash Point: 171.2°C
• Appearance: /
• Density: 1.232g/cm³
• Vapor Pressure: 1.34E-05mmHg at 25°C
• Refractive Index: 1.603
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(BENZYLOXY)-3-NITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(BENZYLOXY)-3-NITROBENZENE(24318-00-1)
• EPA Substance Registry System: 1-(BENZYLOXY)-3-NITROBENZENE(24318-00-1)

Safety Data

• Hazardous Substances Data: 24318-00-1(Hazardous Substances Data)

Usage

General Description

1-(Benzyloxy)-3-nitrobenzene is an organic compound with the chemical formula C13H11NO3. It is a pale yellow crystalline solid that is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. The presence of a benzyl ether group and a nitro group in its structure gives it a significant aromatic character, and it is often used as a building block for the production of dyes, pigments, and other aromatic compounds. This chemical is also known for its potential application in organic synthesis and is commonly used in research and laboratory settings. Additionally, it is important to handle this chemical with caution as it may be harmful if swallowed, inhaled, or comes into contact with skin or eyes.

InChI:InChI=1/C13H11NO3/c15-14(16)12-7-4-8-13(9-12)17-10-11-5-2-1-3-6-11/h1-9H,10H2

Upstream product

• 554-84-7 meta-nitrophenol 
• 100-44-7 benzyl chloride 
• 402-67-5 3-fluoro-1-nitrobenzene 
• 100-51-6 benzyl alcohol 
• 99-65-0 meta-dinitrobenzene 
• 107623-21-2 1-(benzyloxy)-3-iodobenzene 
• 3118-78-3 potassium-3-nitrophenolate 
• 100-39-0 benzyl bromide 
• 3019-85-0 sodium 3-nitrophenoxide 
• 22900-27-2 benzylphenylmethyl sulfonium fluoroborate 
• 22379-62-0 potassium benzyloxide 

Downstream Products

• 1484-26-0 3-(benzyloxy)aniline 
• 591-27-5 m-Hydroxyaniline 
• 91-68-9 3-diethylaminophenol 
• 55872-35-0 phenyl-N-[3-(phenylmethoxy)phenyl]carboxamide 
• 1061377-62-5 1-(3-benzyloxy-phenyl)-3-(4-fluoro-phenyl)-urea 
• 1523-06-4 3-nitrophenyl acetate 
• 554-84-7 meta-nitrophenol 
• 123104-39-2 N,N'-bis-(3-benzyloxy-phenyl)-hydrazine 
• 2380-94-1 1H-indol-4-ol 
• 127028-11-9 N-<3-(Benzyloxy)phenyl>acetohydroxamsaeure 
• 79966-73-7 2-(2-benzyloxy-6-nitrophenyl)acetonitrile 
• 124245-62-1 bis-(3-benzyloxy-phenyl)-diazene-N-oxide 

Relevant articles and documents

Synthesis of 14C-labeled 4-hydroxyindole as an intermediate for the preparation of (S)-2-14-12-13-(indol-2-[14C]-4-yloxy)-2-hydroxypropylaminol -2-methylpropyl]- phenoxylpyridine-5-carboxamide (LY368842-[indole-14C]) glyco

Synthesis of 4-hydroxyindole labeled with 14C at the 2-position was accomplished based on the vicarious nucleophilic substitution reaction of benzyl-protected 3-nitrophenol with p-chlorophenoxyacetonitrile-[1-14C]. This was followed

A inter-b-aminophenol preparation method

The invention belongs to organic synthesis and chemical raw material preparation technical field, and in particular relates to inter-b-aminophenol and intermediate preparation method, inter-b-aminophenol of the preparation method, comprises the steps of: (1) dinitrobenzene substituted benzyl alcohol generated by the reaction with 1 - benzyloxy - 3 - nitrophenyl; (2) 1 - benzyloxy - 3 - nitrobenzene with acetaldehyde in the foaming PH to acid substituted in the reaction solution, or 1 - benzyloxy - 3 - nitrobenzene with acetaldehyde to replace after the recovery of the solvent of the reaction solution dissolved in the dissolving of the re-dissolved solution in organic solvent, by reducing amination and catalytic debenzylation of hydrogenation generating inter-b-aminophenol. 1 - Benzyloxy - 3 - nitrophenyl without separation and purification, directly with the aldehyde and hydrogen reduction amination and debenzylation of hydrogenation reaction. The method is simple, mild condition, equipment strength requirement is low, not produce waste, environment friendly, easily available raw materials, high yield, is suitable for the large-scale generation.

[Cp?RhCl2]2-catalyzed alkyne hydroamination to 1,2-dihydroquinolines

[Cp?RhCl2]2 catalyzes the formation of 1,2-dihydroquinolines from the reaction of two terminal alkynes and an aniline. This reaction is believed to proceed via an alkyne hydroamination followed by an alkyne insertion.