25566-16-9

Basic information

• Product Name: 3,4-dihydroxyhexane-2,5-dione
• Synonyms: 3,4-dihydroxyhexane-2,5-dione;3,4-Dihydroxy-2,5-hexanedione
• CAS NO: 25566-16-9
• Molecular Formula: C₆H₁₀O₄
• Molecular Weight: 146.1412
• EINECS: 247-106-5
• Mol File: 25566-16-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 74 °C
• Boiling Point: 349.1°Cat760mmHg
• Flash Point: 179.1°C
• Appearance: /
• Density: 1.242g/cm³
• Vapor Pressure: 2.91E-06mmHg at 25°C
• Refractive Index: 1.471
• PKA: 11.61±0.20(Predicted)
• CAS DataBase Reference: 3,4-dihydroxyhexane-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihydroxyhexane-2,5-dione(25566-16-9)
• EPA Substance Registry System: 3,4-dihydroxyhexane-2,5-dione(25566-16-9)

Safety Data

• Hazardous Substances Data: 25566-16-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H10O4/c1-3(7)5(9)6(10)4(2)8/h5-6,9-10H,1-2H3

Upstream product

• 116-09-6 hydroxy-2-propanone 
• 78-98-8 2-oxopropanal 
• 96-26-4 dihydroxyacetone 
• 127-09-3 sodium acetate 
• 75-07-0 acetaldehyde 
• 62-54-4 calcium acetate 
• 127-08-2 potassium acetate 

Downstream Products

• 504-31-4 pyran-2-one 
• 6747-82-6 C₂₀H₂₆N₄O₆ 

Relevant articles and documents

Continuous preparation method of 3, 4-dihydroxy-2, 5-hexanedione

The invention discloses a continuous preparation method of 3, 4-dihydroxy-2, 5-hexanedione. The continuous preparation method comprises the following steps: conveying a reaction raw material into at least one fixed bed reactor which is filled with zinc powder and provided with a jacket through a metering pump, reacting, feeding a reaction liquid flowing out of the fixed bed reactor into a reactionliquid storage tank, and feeding into a subsequent extraction process. The invention discloses the method for continuously preparing 3, 4-dihydroxy-2, 5-hexanedione. An original intermittent kettle type reaction process can be replaced; compared with intermittent reaction technology, the method has advantages of high efficiency, stability, controllability and the like, the preparation efficiencyof 3, 4-dihydroxy-2, 5-hexanedione is more effectively improved by further utilizing a multi-fixed bed series connection technology, the controllability, safety and reaction conversion rate are better, side reactions are effectively inhibited, and the generation amount of three wastes is reduced.

A 3, 4 - dihydroxy - 2, 5 - hexanedione preparation method (by machine translation)

The invention relates to a 3, 4 - dihydroxy - 2, 5 - hexanedione preparation method, characterized in that 1. With 5% -50% acetate solution; 2. Catalyst adds at different times, 5% -40% aldehyde solution, 10% -90% dilute sulfuric acid, acetate solution: catalyst: aldehyde solution: dilute sulfuric acid and the mass ratio of 10 - 300: 0.01 - 300:100: 30 - 300, feeding temperature - 20 - 60 °C, 10 - 80 °C insulation 1 - 24 of H; 3. Ethyl acetate extraction 4 - 20 times, 0.05 - 0.099 mpa distillation 10 - 600 minutes, add ethyl acetate, concentrate with ethyl acetate mass ratio is 1: 0.1 - 5, - 40 - 0 °C crystalline 4 - 72 of H, filtered. The advantage of this invention: 1. The method is simple, stable reaction, little side reaction, easy industrial amplifying; 2. The acidity of the reaction solution to overcome the large, zinc powder with an acid reaction is violent, production of a dangerous problem. (by machine translation)

A PROCESS FOR THE PREPARATION OF 1,4-DIALKYL-2,3-DIOL-1,4-BUTANEDIONE

The present invention relates to a process for the preparation of compounds of a l,4-dialkyl-2,3-diol-l,4-butanedione by a acidic aldol condensation between an alkyl glyoxal and an α-hydroxy ketone.