289903-29-3

Basic information

• Product Name: benzyl N-(4-hydroxy-3-methoxybenzyl)carbamate
• Synonyms: benzyl N-(4-hydroxy-3-methoxybenzyl)carbamate
• CAS NO: 289903-29-3
• Molecular Weight: 287.315
• Mol File: 289903-29-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: benzyl N-(4-hydroxy-3-methoxybenzyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl N-(4-hydroxy-3-methoxybenzyl)carbamate(289903-29-3)
• EPA Substance Registry System: benzyl N-(4-hydroxy-3-methoxybenzyl)carbamate(289903-29-3)

Safety Data

• Hazardous Substances Data: 289903-29-3(Hazardous Substances Data)

Upstream product

• 289903-27-1 (3-Methoxy-4-methoxymethoxy benzyl)carbamic Acid Benzyl Ester 
• 4421-08-3 3-methoxy-4-hydroxybenzonitrile 
• 161196-85-6 3-methoxy-4-(methoxymethyloxy)benzonitrile 
• 210918-31-3 3-methoxy-4-methoxymethoxybenzylamine 
• 7149-10-2 vanillylamine hydrochloride 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 289903-33-9 2-{[4-(benzyloxycarbonylamino)methyl-2-methoxy]phenoxy}acetic acid 
• 119056-15-4 2-(2-methoxy-4-aminomethylphenoxy)-acetic acid 
• 289903-31-7 [4-(Benzyloxycarbonylamino-methyl)-2-methoxy-phenoxy]-acetic Acid Methyl Ester 
• 289903-36-2 4-{4-[(benzyloxycarbonylamino)methyl]-2-methoxyphenoxy}-4-oxobutanoic acid benzyl ester 

Relevant articles and documents

GLYCOSIDE COMPOUND

Compounds of formula (I″) wherein: R11, R12, R13, R14 and R15 are hydrogen, hydroxyl, C1-6 alkyl, C1-6 alkoxy, C1-6 alkyl-carbonyloxy, or a G-O— group, and at least one of R11, R12, R13, R14 and R15 is a G-O— group, wherein G is a saccharide residue,X1 is a single bond, or a methylene group, an ethylene group, a trimethylene group, a vinylene group or —CH═CH—CH2—,X2 is —CO—O— or —O—CO—,p and q are integer ofs 0 to 7, and p+q=0 to 8,Y1 is methylene, ethylene or an alkenylene group having a carbon number of 2 to 15 and 1 to 3 double bonds, andR16 and R17 are hydrogen, methyl or ethyl, or R16 and R17 form a C3-6 cycloalkyl group, are useful as GLP-1 secretion promoting agents.

Phenolic modification as an approach to improve the pharmacology of the 3-acyloxy-2-benzylpropyl homovanillic amides and thioureas, a promising class of vanilloid receptor agonists and analgesics

In order to improve the analgesic activity and pharmacokinetics of thioureas 2 and 3, which we previously developed as potent vanilloid receptor (VR) agonists, we prepared and characterized phenolic modifications of them and of their amide surro-gates (7, 8). The aminoethyl analogue of the amide template 13 was a potent analgesic with an EC50 =0.96 μg/kg in the AA-induced writhing test and with better in vivo stability than the parent phenol. Copyright