29881-14-9Relevant articles and documents
(Salen)Mn(III)-catalyzed chemoselective acylazidation of olefins
Zhang, Liang,Liu, Shuya,Zhao, Zhiguo,Su, Hongmei,Hao, Jingcheng,Wang, Yao
, p. 6085 - 6090 (2018)
We describe a (salen)Mn(iii)-catalyzed three-component reaction of aldehydes, olefins, and sodium azide for the installation of two useful groups (C═O and N3) into the double bond. Traditionally, (salen)Mn(iii) in conjunction with iodosobenzene is a classical catalysis system for epoxidation of olefins. Owing to the highly competitive oxygenation approaches, it is a true challenge to establish a distinct strategy for the exploration of new olefin transformations based on this (salen)Mn(iii) catalysis system. Herein, the key to this (salen)Mn(iii)-catalyzed acylazidation of olefins was the rational application of the distinct reactivity of oxomanganese(v) species which is capable of abstracting a hydrogen atom from a substrate C-H bond. This chemoselective reaction occurred in a precisely designed reaction sequence and tolerates complex molecular structures.
HEPATITIS C VIRUS INHIBITORS
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Page/Page column 108, (2012/04/10)
This disclosure concerns novel compounds of Formula (I) as defined in the specification and compositions comprising such novel compounds. These compounds are useful antiviral agents, especially in inhibiting the function of the NS5A protein encoded by Hepatitis C virus (HCV). Thus, the disclosure also concerns a method of treating HCV related diseases or conditions by use of these novel compounds or a composition comprising such novel compounds
ASYMMETRIC CYCLOPROPANATION
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Page/Page column 13-16, (2010/02/11)
The present invention provides a method for asymmetric cyclopropanation of olefins comprising admixing an olefin, an enantiomerically enriched amino acid derivative, and a (halomethylene)zinc compound under conditions sufficient to produce an enantiomeric