3077-85-8Relevant articles and documents
A new method of nitration of carbazole and its derivatives
Pielichowski,Puszynski
, p. 772 - 774 (1974)
Carbazole and its derivatives were nitrated using cupric nitrate in the presence of acetic acid and acetic anhydride. Under these conditions, carbazole is nitrated to 3-nitrocarbazole, and N-alkylcarbazoles are nitrated to 3.6-dinitro derivatives.
-
Morgan,Mitchell
, p. 3283 (1931)
-
Design, Synthesis and Discovery of N,N’-Carbazoyl-aryl-urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication
Spizzichino, Sharon,Mattedi, Giulio,Lauder, Kate,Valle, Coralie,Aouadi, Wahiba,Canard, Bruno,Decroly, Etienne,Kaptein, Suzanne J. F.,Neyts, Johan,Graham, Carl,Sule, Zakary,Barlow, David J.,Silvestri, Romano,Castagnolo, Daniele
supporting information, p. 385 - 390 (2020/01/24)
The recent outbreaks of Zika virus (ZIKV) infection worldwide make the discovery of novel antivirals against flaviviruses a research priority. This work describes the identification of novel inhibitors of ZIKV through a structure-based virtual screening approach using the ZIKV NS5-MTase. A novel series of molecules with a carbazoyl-aryl-urea structure has been discovered and a library of analogues has been synthesized. The new compounds inhibit ZIKV MTase with IC50 between 23–48 μM. In addition, carbazoyl-aryl-ureas also proved to inhibit ZIKV replication activity at micromolar concentration.
COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME
-
Paragraph 0142-0146, (2019/07/18)
The present invention provides a compound of chemical formula 1 and an organic light emitting device comprising the same. The compound according to the present invention has excellent electrochemical and thermal stability, thereby having excellent lifespan characteristics.COPYRIGHT KIPO 2019