321882-28-4

Basic information

• Product Name: 3'-azido-3'-deoxy-5'-O-DMT-2'-O-4'-C-methylenethymidine
• Synonyms: 3'-azido-3'-deoxy-5'-O-DMT-2'-O-4'-C-methylenethymidine
• CAS NO: 321882-28-4
• Molecular Weight: 597.627
• Mol File: 321882-28-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3'-azido-3'-deoxy-5'-O-DMT-2'-O-4'-C-methylenethymidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-azido-3'-deoxy-5'-O-DMT-2'-O-4'-C-methylenethymidine(321882-28-4)
• EPA Substance Registry System: 3'-azido-3'-deoxy-5'-O-DMT-2'-O-4'-C-methylenethymidine(321882-28-4)

Safety Data

• Hazardous Substances Data: 321882-28-4(Hazardous Substances Data)

Upstream product

• 1430073-61-2 3'-azido-5'-O-benzoyl-3'-deoxy-2'-O-4'-C-methylenethymidine 
• 1430073-60-1 3'-azido-3'-deoxy-5'-O-methanesulfonyl-2'-O,4'-C-methylenethymidine 
• 1430073-59-8 2'-O-acetyl-3'-azido-3'-deoxy-5'-O-methanesulfonyl-4'-C-methanesulfonyloxymethyl-thymidine 
• 474927-08-7 3-azido-1,2-di-O-acetyl-5-O-methylsulfonyl-4-[(methylsulfonyloxy)methyl]-α,β-D-erythro-pentofuranose 
• 65-71-4 thymin 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 247025-17-8 3′-azido-3′-deoxy-2′-O,4′-C-methylene-5-methyluridine 

Downstream Products

• 1430073-73-6 1-(3'-deoxy-5'-O-DMT-2'-O,4'-C-methylenethymidin-3'-yl)-4-(3-O-β-cyanoethyl-N,N-diisopropylphosphoramidite-5-deoxy-β-thymidin-5-yl)mercaptoacetamide 
• 1430073-72-5 1-(3'-deoxy-5'-O-DMT-2'-O,4'-C-methylenethymidin-3'-yl)-4-(5-deoxy-2-O,4-C-methylenethymidin-5-yl)mercaptoacetamide 
• 1430073-70-3 1-(3'-deoxy-5'-O-DMT-2'-O,4'-C-methylenethymidin-3'-yl)-4-(5-deoxy-β-thymidin-5-yl)mercaptoacetamide 
• 1430073-67-8 1-(3'-deoxy-5'-O-DMT-2'-O,4'-C-methylenethymidin-3'-yl)-4-(5-deoxy-3-O-tert-butyldiphenylsilyl-β-thymidin-5-yl)mercaptoacetamide 
• 391259-82-8 C₄₉H₆₂N₅O₁₄PSi 
• 391259-84-0 C₄₃H₄₈N₅O₁₄P 
• 321882-29-5 3'-amino-3'-deoxy-5'-O-DMT-2'-O-4'-C-methylenethymidine 

Relevant articles and documents

3′-amino-2′,4′-BNA: Novel bridged nucleic acids having an N3′→P5′ phosphoramidate linkage

Novel oligonucleotide analogues, containing a 3′-amino-2′,4′-BNA unit, were successfully synthesized, and they showed superior duplex and triplex forming ability as well as BNA itself, along with remarkable enzymatic stability.

NOVEL BICYCLONUCLEOSIDE ANALOGUES

This invention provides novel bicyclonucleoside analogues which exhibit anti-AIDS activity and intermediates to produce oligonucleotide analogues which have anti-sense or anti-gene activity as well as in vivo stability. The present invention is compounds