329773-33-3

Basic information

• Product Name: Benzoic acid,4-[[(5-Methoxy-5-oxopentyl)[2-[2-[[4-(2-phenylethyl)phenyl]Methoxy]phenyl]ethyl]aMino]Methyl]-, Methyl ester
• Synonyms: Benzoic acid,4-[[(5-Methoxy-5-oxopentyl)[2-[2-[[4-(2-phenylethyl)phenyl]Methoxy]phenyl]ethyl]aMino]Methyl]-, Methyl ester;Methyl 4-(((5-methoxy-5-oxopentyl)(2-((4-phenethylbenzyl)oxy)phenethyl)amino)methyl)benzoate
• CAS NO: 329773-33-3
• Molecular Formula: C₃₈H₄₃NO₅
• Molecular Weight: 593.75172
• Mol File: 329773-33-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 680.5±55.0 °C(Predicted)
• Appearance: /
• Density: 1.130±0.06 g/cm3(Predicted)
• PKA: 7.82±0.50(Predicted)
• CAS DataBase Reference: Benzoic acid,4-[[(5-Methoxy-5-oxopentyl)[2-[2-[[4-(2-phenylethyl)phenyl]Methoxy]phenyl]ethyl]aMino]Methyl]-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid,4-[[(5-Methoxy-5-oxopentyl)[2-[2-[[4-(2-phenylethyl)phenyl]Methoxy]phenyl]ethyl]aMino]Methyl]-, Methyl ester(329773-33-3)
• EPA Substance Registry System: Benzoic acid,4-[[(5-Methoxy-5-oxopentyl)[2-[2-[[4-(2-phenylethyl)phenyl]Methoxy]phenyl]ethyl]aMino]Methyl]-, Methyl ester(329773-33-3)

Safety Data

• Hazardous Substances Data: 329773-33-3(Hazardous Substances Data)

Upstream product

• 1476774-37-4 methyl 4-((2-(2-((4-phenethylbenzyl)oxy)phenyl)acetamido)methyl)benzoate 
• 6232-11-7 methyl 4-(aminomethyl)benzoate hydrochloride 
• 108-55-4 glutaric anhydride, 
• 1501-27-5 Pentanedioic acid, monomethyl ester 
• 1476774-57-8 2-(2-((4-phenethylbenzyl)oxy)phenyl)acetic acid 
• 1476774-36-3 methyl 2-(2-((4-phenethylbenzyl)oxy)phenyl)acetate 
• 614-75-5 2-Hydroxyphenylacetic acid 
• 56-91-7 p-aminomethylbenzoic acid 
• 14518-67-3 methyl 4-(phenylethyl)benzoate 
• 22446-37-3 methyl (2-hydroxyphenyl)acetate 
• 79757-91-8 1-(bromomethyl)-4-phenethylbenzene 
• 34224-29-8 (4-phenethylphenyl)methanol 
• 1476774-39-6 methyl 4-((5-methoxy-5-oxo-N-(2-((4-phenethylbenzyl)oxy)phenethyl)pentanamido)methyl)benzoate 
• 1501-26-4 methyl 4-(chlorocarbonyl)butyrate 

Downstream Products

• 646995-35-9 4-[[(4-carboxybutyl)-[2-[2-[[4-(2-phenylethyl)phenyl]methoxy]phenyl]ethyl]amino]methyl]benzoic acid hydrochloride 

Relevant articles and documents

Insights into soluble guanylyl cyclase activation derived from improved heme-mimetics

Recently, the structure of BAY 58-2667 bound to the Nostoc sp. H-NOX domain was published. On the basis of this structural information, we designed BAY 58-2667 derivatives and tested their effects on soluble guanylyl cyclase (sGC) activity. Derivative 20 activated sGC 4.8-fold more than BAY 58-2667. Co-crystallization of 20 with the Ns H-NOX domain revealed that the increased conformational distortion at the C-terminal region of αF helix containing 110-114 residues contributes to the higher activation triggered by 20.