79757-91-8

Basic information

• Product Name: 1-(bromomethyl)-4-phenethylbenzene
• Synonyms: 1-(bromomethyl)-4-phenethylbenzene
• CAS NO: 79757-91-8
• Molecular Weight: 275.188
• Mol File: 79757-91-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(bromomethyl)-4-phenethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(bromomethyl)-4-phenethylbenzene(79757-91-8)
• EPA Substance Registry System: 1-(bromomethyl)-4-phenethylbenzene(79757-91-8)

Safety Data

• Hazardous Substances Data: 79757-91-8(Hazardous Substances Data)

Upstream product

• 14518-67-3 methyl 4-(phenylethyl)benzoate 
• 34224-29-8 (4-phenethylphenyl)methanol 

Downstream Products

• 329773-33-3 methyl 4-(((5-methoxy-5-oxopentyl)(2-((4-phenethylbenzyl)oxy)phenethyl)amino)methyl)benzoate 
• 646995-35-9 4-[[(4-carboxybutyl)-[2-[2-[[4-(2-phenylethyl)phenyl]methoxy]phenyl]ethyl]amino]methyl]benzoic acid hydrochloride 
• 1128268-04-1 Ethyl 1-[6-(2-{[4-(2-phenylethyl)benzyl]oxy}phenyl)pyridin-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate 

Relevant articles and documents

Insights into soluble guanylyl cyclase activation derived from improved heme-mimetics

Recently, the structure of BAY 58-2667 bound to the Nostoc sp. H-NOX domain was published. On the basis of this structural information, we designed BAY 58-2667 derivatives and tested their effects on soluble guanylyl cyclase (sGC) activity. Derivative 20 activated sGC 4.8-fold more than BAY 58-2667. Co-crystallization of 20 with the Ns H-NOX domain revealed that the increased conformational distortion at the C-terminal region of αF helix containing 110-114 residues contributes to the higher activation triggered by 20.