39589-66-7Relevant articles and documents
Detection of 2-substituted cyclobutanones as irradiation products of lipid-containing foods: Synthesis and applications of cis- and trans-2-(tetradec-5′-enyl)cyclobutanones and 11-(2′-oxocyclobutyl)-undecanoic acid
Hamilton, Lynne,Stevenson, M. Hilary,Boyd, Derek R.,Brannigan, Ian N.,Treacy, Alan B.,Hamilton, John T. G.,McRoberts, W. Colin,Elliott, Christopher T.
, p. 139 - 146 (1996)
cis- (3cis) and trans-2-(tetradec-5′-enyl)cyclobutanone (3trans) have been chemically synthesised and used in the unambiguous identification of the cis isomer 3cis in irradiated meat (example chicken) and fruit (example pa
Highly selective iridium-catalyzed asymmetric hydrogenation of trifluoromethyl olefins: A new route to trifluoromethyl-bearing stereocenters
Engman, Mattias,Cheruku, Pradeep,Tolstoy, Paeivi,Bergquist, Jonas,Voelker, Sebastian F.,Andersson, Pher G.
supporting information; experimental part, p. 375 - 378 (2009/11/30)
Fluorine-containing compounds are useful in many applications ranging from pharmaceuticals to ferroelectric crystals. We have developed a new, highly enantioselective synthetic route to trifluoromethyl-bearing stereocenters in up to 96% ee via asymmetric hydrogenation using N,P-ligated iridium catalysts. We also hydrogenated an isomeric mixture of olefins; this reaction gave the hydrogenation product highly enantioselectively (87% ee), and only the E isomer was present after the reaction had reached 56% conversion.