40864-08-2

Basic information

• Product Name: 2-(BENZYLOXY)PYRIDINE
• Synonyms: 2-(BENZYLOXY)PYRIDINE;2-phenylmethoxypyridine
• CAS NO: 40864-08-2
• Molecular Formula: C₁₂H₁₁NO
• Molecular Weight: 185.22
• Mol File: 40864-08-2.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 289.5 °C at 760 mmHg
• Flash Point: 106.2 °C
• Appearance: /
• Density: 1.106 g/cm³
• Vapor Pressure: 0.00381mmHg at 25°C
• Refractive Index: 1.577
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(BENZYLOXY)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(BENZYLOXY)PYRIDINE(40864-08-2)
• EPA Substance Registry System: 2-(BENZYLOXY)PYRIDINE(40864-08-2)

Safety Data

• Hazardous Substances Data: 40864-08-2(Hazardous Substances Data)

Usage

General Description

2-(Benzyloxy)pyridine is a chemical compound with the molecular formula C12H11NO. It is a pyridine derivative in which a benzyloxy group is attached to the 2-position of the pyridine ring. 2-(BENZYLOXY)PYRIDINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in organic synthesis to create a variety of different compounds. 2-(Benzyloxy)pyridine is a clear liquid with a slightly yellow tint, and it is flammable and may cause skin and eye irritation upon contact. It should be handled and stored with proper safety precautions.

InChI:InChI=1/C12H11NO/c1-2-6-11(7-3-1)10-14-12-8-4-5-9-13-12/h1-9H,10H2

Upstream product

• 142-08-5 2-Pyridone 
• 100-39-0 benzyl bromide 
• 106-95-6 allyl bromide 
• 100-51-6 benzyl alcohol 
• 142-08-5 2-hydroxypyridin 
• 100-44-7 benzyl chloride 
• 109-04-6 2-bromo-pyridine 
• 5029-67-4 2-iodopyridine 
• 83664-33-9 2-(benzyloxy)-5-bromopyridine 
• 108-88-3 toluene 
• 100-70-9 2-Cyanopyridine 
• 5159-41-1 2-iodobenzyl alcohol 
• 372-48-5 2-fluoropyridine 
• 110-91-8 morpholine 

Downstream Products

• 1753-62-4 N-benzyl-2-pyridone 
• 1044501-41-8 1-(4-methylbenzyl)pyridin-2(1H)-one 
• 46734-13-8 N,N-dimethyl-4-(phenylmethyl)benzenamine 
• 142-08-5 2-hydroxypyridin 
• 56546-36-2 (2-oxo-2H-pyridin-1-yl)-acetic acid 
• 80056-43-5 (2-oxo-2H-pyridin-1-yl)-acetic acid ethyl ester 
• 31796-72-2 phenyl(2-pyridinyl)methanol 
• 142-08-5 2-Pyridone 
• 177559-86-3 diethyl 2-(3-benzyloxypyridinium)-3-thioniumhept-4-thia-2-enoate 
• 5280-02-4 1-(benzyloxy)pyridin-2(1H)-one 
• 822-89-9 1-Hydroxy-2-pyridon 
• 7278-60-6 benzyl 3-cholesteryl ether 
• 103-50-4 dibenzyl ether 
• 888709-54-4 1-benzyloxy-4-(p-methoxyphenyl)butane 

Relevant articles and documents

Method for synthesizing aryl benzyl ether compound

The invention discloses a method for synthesizing aryl benzyl ether compounds, which comprises the following steps: by using an iron (III) complex containing 1, 3-di-tert-butyl imidazole cations and having a molecular formula of [(tBuNCH = CHNtBu) CH] [FeBr4] as a catalyst and di-tert-butyl peroxide as an oxidant, carrying out oxidative coupling reaction on phenolic compounds and toluene compounds to synthesize the corresponding aryl benzyl ether compounds. The method is the first example for preparing the aryl benzyl ether compound through the oxidative coupling reaction of the phenolic compound and the toluene compound, which is realized by an iron-based catalyst, and has the advantages of atom economy, environmental friendliness and good substrate applicability.

A facile and versatile electro-reductive system for hydrodefunctionalization under ambient conditions

A general electrochemical system for reductive hydrodefunctionalization is described, employing the inexpensive and easily available triethylamine (Et3N) as a sacrificial reductant. This protocol is characterized by facile operation, sustainable conditions, and exceptionally wide substrate scope covering the cleavage of C-halogen, N-S, N-C, O-S, O-C, C-C and C-N bonds. Notably, the selectivity and capability of reduction can be conveniently switched by simple incorporation or removal of an alcohol as a co-solvent.

Environmentally benign nucleophilic substitution reaction of arylalkyl halides in water using CTAB as the inverse phase transfer catalyst

An environmentally benign, practically scalable and highly selective C-arylalkylation of active methylene compounds is developed using CTAB as the inverse phase transfer catalyst in water. The methodology developed is elaborated into the one-pot synthesis of quinoline derivatives and also applicable to the regioselective N-aralkyl of 2-pyridones.