42772-85-0

Basic information

• Product Name: 2-(4-Methylphenyl)sulfonyloxyethanol
• Synonyms: 2-(4-Methylphenyl)sulfonyloxyethanol;2-HYDROXYETHYL 4-METHYLBENZENESULFONATE
• CAS NO: 42772-85-0
• Molecular Formula: C₉H₁₂O₄S
• Molecular Weight: 216.25418
• Mol File: 42772-85-0.mol
• Article Data: 39

Chemical Properties

• Melting Point: 135-136 °C
• Boiling Point: 376.8°C at 760 mmHg
• Flash Point: 181.7°C
• Appearance: /
• Density: 1.288g/cm³
• Vapor Pressure: 2.39E-06mmHg at 25°C
• Refractive Index: 1.54
• PKA: 13.76±0.10(Predicted)
• CAS DataBase Reference: 2-(4-Methylphenyl)sulfonyloxyethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Methylphenyl)sulfonyloxyethanol(42772-85-0)
• EPA Substance Registry System: 2-(4-Methylphenyl)sulfonyloxyethanol(42772-85-0)

Safety Data

• Hazardous Substances Data: 42772-85-0(Hazardous Substances Data)

Usage

General Description

2-(4-methylphenyl)sulfonyloxyethanol is a chemical compound with the molecular formula C9H12O4S. It is a sulfonyloxyethanol derivative and contains a sulfonyloxy group attached to a phenyl group. This chemical is commonly used as a reagent for the synthesis of other organic compounds, and it may have potential applications in pharmaceutical and industrial processes. Additionally, 2-(4-methylphenyl)sulfonyloxyethanol may have properties that make it useful in the field of organic chemistry, and its molecular structure suggests it has potential as a building block for the preparation of various types of compounds. Further research may reveal additional properties and potential uses of this chemical.

InChI:InChI=1/C9H12O4S/c1-8-2-4-9(5-3-8)14(11,12)13-7-6-10/h2-5,10H,6-7H2,1H3

Upstream product

• 96-49-1 [1,3]-dioxolan-2-one 
• 6192-52-5 p-toluenesulfonic acid monohydrate 
• 6123-63-3 4-acetyl-5-methyl-1-phenylpyrazole 
• 107-21-1 ethylene glycol 
• 542-59-6 2-hydroxyethyl acetate 
• 98-59-9 p-toluenesulfonyl chloride 
• 104-15-4 toluene-4-sulfonic acid 
• 75-21-8 oxirane 
• 7182-86-7 tetrabutylammonium p-toluenesulfonate 

Downstream Products

• 115147-99-4 C₂₈H₄₂O₈S₂ 
• 115147-98-3 C₂₆H₃₈O₈S₂ 
• 958233-17-5 2-(4-(3-(2-(diethylamino)-2-oxoethyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-yl)phenoxy)ethyl 4-methylbenzenesulfonate 
• 80158-32-3 (E)-ω,ω'-(1,2-Diphenylethendiyldioxy)bis(2-ethoxyethanol)-bis(p-toluolsulfonat) 
• 80158-33-4 (1R*,2R*)-ω,ω'-(1,2-Diphenylethandiyldioxy)bis(2-ethoxyethanol)-bis(p-toluolsulfonat) 
• 958641-66-2 6-bromo-2-[4'-(2''-p-toluenesulfonyloxyethoxy)phenyl]imidazo[1,2-a]pyridine 
• 1258047-78-7 C₁₇H₂₂O₈S 
• 1258047-89-0 C₁₄H₁₈O₆S 
• 1517-05-1 2-azidoethanol 
• 67521-22-6 4-(2-hydroxyethoxy)-styrene 
• 1711-24-6 4-(2-hydroxyethoxy)benzoic acid 
• 25781-99-1 3-(2-hydroxyethoxy)benzoic acid 
• 55211-84-2 2-(2-hydroxyethoxy)benzoic acid 
• 148400-72-0 2-[tert-butyl(dimethyl)silyl]oxyethyl 4-methylbenzenesulfonate 

Relevant articles and documents

Pd/Cu-Catalyzed Vinylation of Terminal Alkynes with (2-Bromoethyl)diphenylsulfonium Triflate

The potential of (2-bromoethyl)diphenylsulfonium triflate to be a powerful vinylation reagent was determined by the Sonogashira cross-coupling reactions with terminal alkynes. The vinylation proceeded smoothly at 25 °C under Pd/Cu catalysis to afford a variety of 1- and 2-unsubstituted 1,3-enynes in moderate to excellent yields. This protocol represents the first application of (2-haloethyl)diphenylsulfonium triflate as a CH═CH2 transfer source in organic synthesis.

NOVEL COMPOUND For Organic light emitting diode AND COATING COMPOSITION FOR ORGANIC LAYER COMPRISING THE SAME

Provided are a compound represented by chemical formula (1) and a coating liquid composition comprising the same. The above formula (1) is as described in the description of the invention.

Pegylated triarylmethanes: Synthesis, antimicrobial activity, anti-proliferative behavior and in silico studies

We describe herein the synthesis, characterization and biological studies of novel PEGylated triarylmethanes. Non-symmetrical and symmetrical triarylmethanes series have been synthesized by Friedel-Crafts hydroxyalkylation or directly from bisacodyl respectively followed by a functionalization with PEG fragments in order to increase bioavailability and biological effectiveness. The antimicrobial activity was investigated against Gram-positive and Gram-negative foodborne pathogens and against Candida albicans, an opportunistic pathogenic yeast. The anti-biocidal activity was also studied using Staphylococcus aureus as a reference bacterium. Almost all PEGylated molecules displayed an antifungal activity comparable with fusidic acid with MIC values ranging from 6.25 to 50 μg/mL. Compounds also revealed a promising antibiofilm activity with biofilm eradication percentages values above 80% for the best molecules (compounds 4d and 7). Compounds 7 and 8b showed a modest antiproliferative activity against human colorectal cancer cell lines HT-29. Finally, in silico molecular docking studies revealed DHFR and DNA gyrase B as potential anti-bacterial targets and in silico predictions of ADME suggested adequate drug-likeness profiles for the synthetized triarylmethanes.