4362-22-5

Basic information

• Product Name: 1,3-DIOXOLANE, 2-(1-PHENYLETHYL)
• Synonyms: 3-Dioxolane,2-(1-phenylethyl)-1;RARECHEM AL BP 0123;1,3-DIOXOLANE, 2-(1-PHENYLETHYL);HYDRATROPIC ALDEHYDE CYCLOGLYCOL ACETAL;2-(1-phenylethyl)-1,3-dioxolane;2-(1-phenylethyl)-3-dioxolane
• CAS NO: 4362-22-5
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.23
• EINECS: 224-449-9
• Mol File: 4362-22-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 249.4°Cat760mmHg
• Flash Point: 106.8°C
• Appearance: /
• Density: 1.071g/cm³
• Vapor Pressure: 0.0363mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: 1,3-DIOXOLANE, 2-(1-PHENYLETHYL)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-DIOXOLANE, 2-(1-PHENYLETHYL)(4362-22-5)
• EPA Substance Registry System: 1,3-DIOXOLANE, 2-(1-PHENYLETHYL)(4362-22-5)

Safety Data

• Hazardous Substances Data: 4362-22-5(Hazardous Substances Data)

Usage

Definition

ChEBI: A dioxolane that is 1,3-dioxolane substituted by a 1-phenylethyl group at position 2.

InChI:InChI=1/C11H14O2/c1-9(11-12-7-8-13-11)10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3

Upstream product

• 34713-70-7 2-Phenylpropanal 
• 107-21-1 ethylene glycol 
• 85459-20-7 (α-methylbenzyl)zinc bromide 
• 265134-89-2 1-(1,3-dioxolan-2-yl)-1H-1,2,3-benzotriazole 
• 100-42-5 styrene 
• 201230-82-2 carbon monoxide 
• 536-74-3 phenylacetylene 

Downstream Products

• 80550-06-7 2-hydroxyethyl-2-phenylpropanoate 

Relevant articles and documents

Visible-light-induced acetalization of aldehydes with alcohols

In this work, we have achieved a simple and general method for acetalization of aldehydes by means of a photochemical reaction under low-energy visible light irradiation. A broad range of aromatic, heteroaromatic, and aliphatic aldehydes have been protected under neutral conditions in good to excellent yields using a catalytic amount of Eosin Y as the photocatalyst. Our visible light mediated acetalization strategies are successful for more challenging acid-sensitive aldehydes and sterically hindered aldehydes. Notably, this protocol is chemoselective to aldehydes, while ketones remain intact.

A mild, room-temperature protection of ketones and aldehydes as 1,3-dioxolanes under basic conditions

Protection of ketones or aldehydes as 1,3-dioxolane derivatives proceeds within minutes at room temperature in the presence of N- hydroxybenzenesulfonamide, its O-benzyl derivative, or the tosyl analogue, in the absence of strong protonic acids, and in the presence of base (Et). Acid-sensitive groups such as O-THP, O-TBS, or N-Boc are unaffected. Copyright

Acetalization of carbonyl compounds catalyzed by bismuth triflate under solvent-free conditions

Carbonyl compounds were converted to the corresponding 1,3-dioxolanes and 1,3-dioxanes with ethylene glycol and 1,3-propandiol in the presence of bismuth triflate under solvent-free conditions. In addition, high chemoselective protection of aldehydes in the presence of ketones has been achieved.