500992-02-9

Basic information

• Product Name: Butanamide, N-[4-nitro-2-(phenylethynyl)phenyl]-
• CAS NO: 500992-02-9
• Molecular Formula: C18H16N2O3
• Molecular Weight: 308.337
• Mol File: 500992-02-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Butanamide, N-[4-nitro-2-(phenylethynyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanamide, N-[4-nitro-2-(phenylethynyl)phenyl]-(500992-02-9)
• EPA Substance Registry System: Butanamide, N-[4-nitro-2-(phenylethynyl)phenyl]-(500992-02-9)

Safety Data

• Hazardous Substances Data: 500992-02-9(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 500991-95-7 N-[4'-nitro-2'-(((trifluoromethane)sulfonyl)oxy)phenyl]butyramide 
• 141-75-3 butyryl chloride 
• 165280-21-7 4-nitro-2-(2-phenylethynyl)aniline 

Downstream Products

• 6855-64-7 2-phenyl-1H-indol-5-amine 
• 4993-87-7 5-nitro-2-phenyl-1H-indole 

Relevant articles and documents

Modulators of ATP-binding cassette transporters

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

Chemistry of aminophenols. Part 2: A general and efficient synthesis of indoles possessing a nitrogen substituent at the C4, C5, C6, and C7 positions

A general and efficient synthesis of indoles possessing a nitrogen substituent at the C4, C5, C6, and C7 positions has been developed. Starting from commercially available nitro 2-aminophenols, 5-, 6-, and 7-arenesulfamoylindoles were synthesized via a ba