502442-65-1

Basic information

• Product Name: ethyl (2R,4R)-N-tert-butyloxycarbonyl-4-tert-butyldiphenylsiloxyprolinate
• CAS NO: 502442-65-1
• Molecular Weight: 497.707
• Mol File: 502442-65-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl (2R,4R)-N-tert-butyloxycarbonyl-4-tert-butyldiphenylsiloxyprolinate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2R,4R)-N-tert-butyloxycarbonyl-4-tert-butyldiphenylsiloxyprolinate(502442-65-1)
• EPA Substance Registry System: ethyl (2R,4R)-N-tert-butyloxycarbonyl-4-tert-butyldiphenylsiloxyprolinate(502442-65-1)

Safety Data

• Hazardous Substances Data: 502442-65-1(Hazardous Substances Data)

Upstream product

• 77450-00-1 (2R,4R)-4-hydroxyproline-1,2-dicarboxylic acid 1-tert-butyl 2-ethyl ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 2584-71-6 cis-hydroxy-D-proline 
• 132666-67-2 (2S,4R)-ethyl 4-hydroxypyrrolidine-2-carboxylate 
• 502442-59-3 ethyl (4R)-2-(N-tert-butyloxycarbonylamino)-5-tert-butyldimethylsiloxy-4-tert-butyldiphenylsiloxy-2-pentenoate 
• 502442-61-7 ethyl (4R)-2-(N-tert-butyloxycarbonylamino)-4-tert-butyldiphenylsiloxy-5-hydroxy-2-pentenoate 
• 502442-57-1 ethyl (4R)-2-(N-tert-butyloxycarbonylamino)-5-tert-butyldimethylsiloxy-2-pentenoate 
• 502442-54-8 ethyl (4R)-2-(N-tert-butyloxycarbonylamino)-4,5-dihydroxy-2-pentenoa 

Downstream Products

• 135042-12-5 (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-D-proline 

Relevant articles and documents

Enantioselective synthesis of 4-hydroxy-D-pyroglutamic acid derivatives by an asymmetric 1,3-dipolar cycloaddition

The 1,3-dipolar cycloaddition of a chiral nitrone derived from glyoxylic acid and protected D-ribosyl hydroxylamine with the acrylamide of Oppolzer's sultam provides a perfectly stereoselective approach to protected (2R,4R)-4-hydroxy-D-pyroglutamic acid.