51307-68-7

Basic information

• Product Name: N-4-chlorobenzylhydroxylamine
• Synonyms: N-4-chlorobenzylhydroxylamine
• CAS NO: 51307-68-7
• Molecular Weight: 157.6
• Mol File: 51307-68-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N-4-chlorobenzylhydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-4-chlorobenzylhydroxylamine(51307-68-7)
• EPA Substance Registry System: N-4-chlorobenzylhydroxylamine(51307-68-7)

Safety Data

• Hazardous Substances Data: 51307-68-7(Hazardous Substances Data)

Upstream product

• 3848-36-0 4-chlorobenzaldoxime 
• 7647-01-0 hydrogenchloride 
• 711014-90-3 N-(4-chlorophenyl)methyl-N-(4-chlorophenyl)methyleneamine N-oxide 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 55606-33-2 N-(benzylidene)-4-chlorobenzylamine N-oxide 
• 1391090-18-8 1-(4-chlorophenyl)-N-cyclopentylidenemethanamine oxide 
• 1391090-04-2 benzyl (2-(N-(4-chlorobenzyl)-2,2,2-trifluoroacetamido)cyclopent-2-en-1-yl)carbamate 
• 1453196-66-1 (S)-5-benzyl-2-(4-chlorobenzyl)-3-methyl-1,2,5-oxadiazinan-6-one 
• 1453196-48-9 (S)-N¹-benzyl-N²-(4-chlorobenzyl)-N²-hydroxypropane-1,2-diamine 
• 287482-35-3 N,N'-(ethane-1,2-diylidene)bis[(4-chlorophenyl)methanamine oxide] 

Relevant articles and documents

Highly enantioselective intermolecular hydroamination of allylic amines with chiral aldehydes as tethering catalysts

Chirally LinkedIn: Chiral aldehydes are effective tethering catalysts for enantioselective intermolecular hydroamination, which provides access to vicinal diamine motifs in good yields and excellent enantioselectivities (see scheme). This work highlights simple chiral α-oxygenated aldehydes as effective organocatalysts capable of efficiently inducing asymmetry through transient intramolecularity. Copyright

A novel one-pot reductive amination of aldehydes and ketones with lithium perchlorate and zirconium borohydride-piperazine complexes

A novel, one-pot reductive mono-alkylation method of amines (primary and secondary), 1,2-phenylenediamine, O-trimethylsilylhydroxylamine, and N,N-dimethylhydrazine was developed using LiClO4 (5 mol %) as a source for in situ generation of imine

Synthesis and tyrosinase inhibitory activity of novel N-hydroxybenzyl-N-nitrosohydroxylamines

Several novel N-substituted N-nitrosohydroxylamines were synthesized. They all inhibited mushroom tyrosinase, but the type of inhibition was different depending on the substituent. Some N-(mono- or dihydroxybenzyl)-N-nitrosohydroxylamines exhibited uncompetitive inhibition with respect to L-dopa. Among them, compound 6 was also a competitive inhibitor with respect to oxygen. This observation suggests that another interaction by the meta- or para-hydroxyl group might stabilize the binding of the inhibitor to the enzyme through the oxygen binding site.