51498-55-6

Basic information

• Product Name: Piperidine, 1-methyl-2-(phenylethynyl)-
• CAS NO: 51498-55-6
• Molecular Formula: C14H17N
• Molecular Weight: 199.296
• Mol File: 51498-55-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Piperidine, 1-methyl-2-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1-methyl-2-(phenylethynyl)-(51498-55-6)
• EPA Substance Registry System: Piperidine, 1-methyl-2-(phenylethynyl)-(51498-55-6)

Safety Data

• Hazardous Substances Data: 51498-55-6(Hazardous Substances Data)

Upstream product

• 931-20-4 1-methylpiperidin-2-one 
• 536-74-3 phenylacetylene 
• 25355-41-3 1-methyl-6-methylsulfanyl-2,3,4,5-tetrahydro-pyridinium; iodide 
• 13070-07-0 1-methylpiperidine-2-thione 
• 1191-30-6 5-bromopentanal 

Downstream Products

• 125039-05-6 benzyl 1-methylpiperidin-2-yl ketone 
• 101113-68-2 (+/-)-sedaminone 

Relevant articles and documents

Two-Step Catalytic Transformation of N-Benzyllactams to Alkaloids (±)-Solenopsin, (±)-Solenopsin A, and (+)-Julifloridine

We report herein that the Ir and CuI bis-metal catalyzed reductive alkynylation of amides, a method that we developed previously, can be extended to 6-, 7-, and 8-membered lactams. The catalytic reductive alkynylation of 6-methyl-2-piperidinone

First synthesis of medium-sized ring allenyl lactams

Medium-sized lactams bearing an axially chiral allene unit have been synthesized by using an aza-ketene Claisen rearrangement. Starting from 2-alkynylpiperidines or 2-alkynylazepines, ring enlargement enabled the highly diastereoselective formation of 10-

Alkynylation of Thiolactams. New Synthesis of α-Substituted Pyrrolidine and Piperidine Alkaloids

Alkynylation of S-alkylthioamidium salts of thiolactams with lithium acetylides followed by reduction with LiAlH4 provided α-alkynylazacycloalkanes, which on reduction, or hydroboration followed by oxidation, gave α-substituted pyrrolidine and piperidine alkaloids.