534599-19-4Relevant articles and documents
Chemoenzymatic synthesis and binding affinity of novel (R)- and (S)-3-aminomethyl-1-tetralones, potential atypical antipsychotics
Caro, Yolanda,Torrado, Maria,Masaguer, Christian F.,Ravina, Enrique,Padin, Fernando,Brea, Jose,Loza, Maria I.
, p. 585 - 589 (2007/10/03)
A series of (R)- and (S)-3-aminomethyl-1-tetralones, conformationally constrained analogues of haloperidol, have been obtained by enzymatic resolution of the corresponding racemic 3-hydroxymethyl-1-tetralones using Pseudomonas fluorescens lipase. Their bi