576-26-1 Usage
Chemical Properties
colourless crystals or white powder. soluble in alcohol, ether, chloroform, benzene and alkali solution, slightly soluble in water.
Occurrence
Reported found in smoked fatty fish, boiled and cooked cured pork, rum, malt whiskey, Japanese whiskey,
coffee, katsuobushi (dried bonito) and lamb’s lettuce (Valerianella locusta).
Uses
Similar to other xylenol compounds, 2,6-dimethylphenol is used in the synthesis of anti-oxidant compounds due to the phenol moiety in the structure. In addition, this compound is used as a a reactant
in the synthesis of polyphenylene ether polymers.
Preparation
From coal tar oil or coal hydrogenation.Synthesis of 2,6-dimethylphenol: The gas-phase catalytic reaction of phenol and methanol is carried out, and then purified by rectification, and the product purity can reach more than 99%.Selective phenol methylation to 2,6-dimethylphenol in a fluidized bed of iron-chromium mixed oxide catalyst with o–cresol circulationCatalytic synthesis of 2,6-dimethylphenol from methanol and cyclohexanone over titanium oxide-supported vanadium oxide catalysts
Application
2,6-dimethylphenol is generally applied in industry as a monomer in polymerization reaction. For the production of polyphenylene ether resins, polyester and polyether resins.
Aroma threshold values
Detection: 400 ppb
General Description
2,6-dimethylphenol is a colorless to off-white crystalline solid with a sweet tarry odor. Odor threshold concentration: 0.4 mg/L . (NTP, 1992)
Reactivity Profile
2,6-Dimethylphenol is incompatible with bases, acid chlorides, acid anhydrides, and oxidizing agents. Corrodes steel, brass, copper, and copper alloys.
Fire Hazard
2,6-Dimethylphenol is combustible.
Flammability and Explosibility
Nonflammable
Purification Methods
Fractionally distil 2,6-xylenol under nitrogen, crystallise it from *benzene or hexane, and sublime it at 38o/10mm. [Beilstein 6 IV 3122.]
Check Digit Verification of cas no
The CAS Registry Mumber 576-26-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,7 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 576-26:
(5*5)+(4*7)+(3*6)+(2*2)+(1*6)=81
81 % 10 = 1
So 576-26-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H10O/c1-6-4-3-5-7(2)8(6)9/h3-5,9H,1-2H3
576-26-1Relevant articles and documents
Impact of oxygen vacancies in Ni supported mixed oxide catalysts on anisole hydrodeoxygenation
Ali, Hadi,Kansal, Sushil Kumar,Lauwaert, Jeroen,Saravanamurugan, Shunmugavel,Thybaut, Joris W.,Vandevyvere, Tom
, (2022/03/02)
The hydrodeoxygenation (HDO) activity of anisole has been investigated over Ni catalysts on mixed metal oxide supports containing Nb–Zr and Ti–Zr in 1:1 and 1:4 ratios. XRD patterns indicate the incorporation of Ti (or Nb) into the ZrO2 framewo
Photocatalytic synthesis of phenols mediated by visible light using KI as catalyst
Huiqin, Wei,Wu, Mei
supporting information, (2021/11/30)
A transition-metal-free hydroxylation of iodoarenes to afford substituted phenols is described. The reaction is promoted by KI under white LED light irradiation and uses atmospheric oxygen as oxidant. By the use of triethylamine as base and solvent, the corresponding phenols are obtained in moderate to good yields. Mechanistic studies suggest that KI and catalysis synergistically promote the cleavage of C-I bond to form free aryl radicals.
Reaction of hydroxyl radical with arenes in solution—On the importance of benzylic hydrogen abstraction
Waggoner, Abygail R.,Abdulrahman, Yahya,Iverson, Alexis J.,Gibson, Ethan P.,Buckles, Mark A.,Poole, James S.
, (2021/08/27)
The regioselectivity of hydroxyl radical reactions with alkylarenes was investigated using a nuclear magnetic resonance (NMR)-based methodology capable of trapping and quantifying addition and hydrogen abstraction products of the initial elementary step of the oxidation process. Abstraction products are relatively minor components of the product mixtures (15–30 mol%), depending on the magnitude of the overall rate coefficient and the number of available hydrogens. The relative reactivity of addition at a given position on the ring depends on its relation to the methyl substituents on the hydrocarbons under study. The reactivity enhancements for disubstituted and trisubstituted rings are approximately additive under the conditions of this study.