5767-55-5

Basic information

• Product Name: ethyl 7-(4-chlorophenyl)-4-(2,5-dimethoxyphenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate
• CAS NO: 5767-55-5
• Molecular Formula: C₂₇H₂₈ClNO₅
• Molecular Weight: 346.426
• Mol File: 5767-55-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 519.8°Cat760mmHg
• Flash Point: 268.1°C
• Density: 1.174g/cm³
• CAS DataBase Reference: ethyl 7-(4-chlorophenyl)-4-(2,5-dimethoxyphenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 7-(4-chlorophenyl)-4-(2,5-dimethoxyphenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate(5767-55-5)
• EPA Substance Registry System: ethyl 7-(4-chlorophenyl)-4-(2,5-dimethoxyphenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate(5767-55-5)

Safety Data

• Hazardous Substances Data: 5767-55-5(Hazardous Substances Data)

Upstream product

• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 5767-53-3 N,N'-bis(3-methoxysalicylidene)-1,3-propanediamine 

Downstream Products

• 1421749-23-6 diethyl-2,2'-(propane-1,3-diylbis((2-hydroxy-3-methoxybenzyl)azanediyl))diacetate 

Relevant articles and documents

A series of hydrogen bond mediated dinuclear nickel(II) complexes with reduced Schiff base ligands: An insight into the nature of their short intermolecular hydrogen bonds

A series of isostructural centrosymmetric hydrogen bonded dimeric nickel(II) complexes of general formula, [Ni2(HL)2(DMSO)2(H2O)2]X {where H2L = N2O4 donor reduced Sch

Salen, reduced salen and N-alkylated salen type compounds: Spectral characterization, theoretical investigation and biological studies

Salen [2,2′-{propane-1,3-diylbis[nitrilo(E)methylylidene]}bis(6- methoxyphenol)], reduced salen [(2,2′-[propane-1,3-diylbis(iminomethylene) )]bis(6-methoxyphenol)] and N-alkylated salen [diethyl-2,2′-(propane-1,3- diylbis((2-hydroxy-3-methoxybenzyl) azanediyl))diacetate] compounds have been synthesized and characterized by IR, 1H NMR, 13C NMR and UV-vis. spectroscopy. Molecular geometry of the title compounds in the ground state has been optimized by density functional method (B3LYP) with 6-31G basis set. Vibrational frequencies of the compounds were computed and compared with the experimental values. Tautomeric stability study of salen inferred that the enolimine form is more stable than its ketoenamine form in gas phase. The spectral behavior of salen in polar and nonpolar solvents was examined demonstrate the positive solvatochromism. The synthesized compounds have been studied with respect to their binding to calf thymus DNA showed that there were interactions between the compounds and DNA through a groove binding mode. Furthermore, the DNA cleavage activity of the compounds has been investigated by gel electrophoresis. The antioxidant properties of compounds were evaluated by DPPH method. The N-alkylated compound has a higher DPPH free radical scavenging activity. The antimicrobial activity was investigated on various gram positive and gram negative bacteria.