58972-42-2

Basic information

• Product Name: 1-(2-hydroxyphenyl)-1-phenyl-ethanol
• Synonyms: 1-(2-hydroxyphenyl)-1-phenyl-ethanol
• CAS NO: 58972-42-2
• Molecular Weight: 214.264
• Mol File: 58972-42-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1-(2-hydroxyphenyl)-1-phenyl-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxyphenyl)-1-phenyl-ethanol(58972-42-2)
• EPA Substance Registry System: 1-(2-hydroxyphenyl)-1-phenyl-ethanol(58972-42-2)

Safety Data

• Hazardous Substances Data: 58972-42-2(Hazardous Substances Data)

Upstream product

• 118-93-4 o-hydroxyacetophenone 
• 108-86-1 bromobenzene 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 39477-86-6 1-phenyl-1-(2-hydroxyphenyl)ethene 
• 1094415-73-2 ethyl 2,4-dimethyl-4-phenyl-4H-chromene-3-carboxylate 
• 1396690-38-2 2-(1-phenylvinyl)phenyl formate 
• 4355-42-4 3-methyl-3-phenylbenzofuran-2(3H)-one 
• 61198-52-5 3,4-dihydro-4-phenyl-2H-1-benzopyran-2-one 
• 15185-05-4 4-phenylcoumarin 
• 1464816-05-4 C₁₇H₁₆O₃ 
• 1464815-30-2 C₁₄H₁₁O^(1-)*Cs⁽¹⁺⁾ 
• 1610359-50-6 1,2,4-triphenylspiro[4,5]deca-1,3,7,9-tetraen-6-one 
• 1644257-90-8 2-methyl-1,4-diphenylspiro[4.5]deca-1,3,7,9-tetraen-6-one 
• 1644257-91-9 1,4-diphenyl-2-propylspiro[4.5]deca-1,3,7,9-tetraen-6-one 
• 1644257-95-3 2-{2-[(tert-butyldimethylsilyl)oxy]ethyl}-1-[(E)-2-(4-methylphenyl)ethenyl]-4-phenylspiro[4.5]deca-1,3,7,9-tetraen-6-one 
• 1644258-00-3 1-ethenyl-4-phenyl-2-(2-phenylethyl)spiro[4.5]deca-1,3,7,9-tetraen-6-one 
• 1644258-01-4 benzyl (2E)-3-{2-Butyl-10-oxo-4-phenylspiro[4.5]deca-1,3,6,8-tetraen-1-yl}prop-2-enoate 

Relevant articles and documents

Asymmetric Hydroesterification of Diarylmethyl Carbinols

An efficient asymmetric hydroesterfication of diarylmethyl carbinols is developed for the first time with a Pd-WingPhos catalyst, resulting in a series of chiral 4-aryl-3,4-dihydrocoumarins in excellent enantioselectivities and good yields. The method features mild reaction conditions, a broad substrate scope, use of easily accessible starting materials, and low palladium loadings. A plausible stereochemical model is also proposed with the Pd-WingPhos catalyst. This method has enabled a 4-step asymmetric synthesis of (R)-tolterodine from readily available starting materials.

One-Step Synthesis of Substituted Benzofurans from ortho- Alkenylphenols via Palladium-Catalyzed C=H Functionalization

A dehydrogenative oxygenation of C(sp2)=H bonds with intramolecular phenolic hydroxy groups has been developed, which provides a straightforward and concise access to structurally diversely benzofurans from ortho-alkenylphenols. The reaction is catalyzed by palladium on carbon (Pd/C) without any oxidants and sacrificing hydrogen acceptors.

Palladium(II)-catalyzed direct carboxylation of alkenyl C-H bonds with CO2

Pd-catalyzed direct carboxylation of alkenyl C-H bonds with carbon dioxide was realized for the first time. Treatment of 2-hydroxystyrenes and a catalytic amount of Pd(OAc)2 with Cs2CO3 under atmospheric pressure of CO2 afforded corresponding coumarins in good yield. Furthermore, isolation of the key alkenylpalladium intermediate via C-H bond cleavage was achieved. The reaction was proposed to undergo reversible nucleophilic addition of the alkenylpalladium intermediate to CO2.