39477-86-6

Basic information

• Product Name: Phenol, 2-(1-phenylethenyl)-
• CAS NO: 39477-86-6
• Molecular Formula: C14H12O
• Molecular Weight: 196.249
• Mol File: 39477-86-6.mol
• Article Data: 35

Chemical Properties

• CAS DataBase Reference: Phenol, 2-(1-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-(1-phenylethenyl)-(39477-86-6)
• EPA Substance Registry System: Phenol, 2-(1-phenylethenyl)-(39477-86-6)

Safety Data

• Hazardous Substances Data: 39477-86-6(Hazardous Substances Data)

Upstream product

• 58972-42-2 1-(2-hydroxyphenyl)-1-phenyl-ethanol 
• 98-86-2 acetophenone 
• 108-95-2 phenol 
• 536-74-3 phenylacetylene 
• 57049-58-8 3-phenyl-2,3-dihydrobenzofuran 
• 32250-84-3 1-(2-methoxy-phenyl)-1-phenyl-ethanol 
• 95-56-7 2-hydroxybromobenzene 
• 14900-39-1 phenylvinylboronic acid 
• 4545-21-5 acetophenone p-toluenesulfonylhydrazone 
• 117-99-7 2-Hydroxybenzophenone 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 5661-50-7 N-(phenoxy)acetamide 
• 108-86-1 bromobenzene 
• 100-42-5 styrene 

Downstream Products

• 120346-43-2 1-(4-hydroxyphenyl)-1-phenylethane 
• 1379805-14-7 C₁₄H₁₂O₂ 
• 1379805-13-6 3-(2-hydroxyphenyl)-3-phenylacrylic acid 
• 15185-05-4 4-phenylcoumarin 
• 117-99-7 2-Hydroxybenzophenone 
• 1464815-30-2 C₁₄H₁₁O^(1-)*Cs⁽¹⁺⁾ 
• 1448251-23-7 C₂₈H₂₁CsO₂Pd 
• 24892-80-6 2-(1-phenylvinyl)anisole 
• 1464815-91-5 C₁₇H₁₆O₃ 
• 1464816-05-4 C₁₇H₁₆O₃ 
• 1610359-50-6 1,2,4-triphenylspiro[4,5]deca-1,3,7,9-tetraen-6-one 
• 1610359-65-3 C₂₈H₁₉⁽²⁾HO 

Relevant articles and documents

Asymmetric Hydroesterification of Diarylmethyl Carbinols

An efficient asymmetric hydroesterfication of diarylmethyl carbinols is developed for the first time with a Pd-WingPhos catalyst, resulting in a series of chiral 4-aryl-3,4-dihydrocoumarins in excellent enantioselectivities and good yields. The method features mild reaction conditions, a broad substrate scope, use of easily accessible starting materials, and low palladium loadings. A plausible stereochemical model is also proposed with the Pd-WingPhos catalyst. This method has enabled a 4-step asymmetric synthesis of (R)-tolterodine from readily available starting materials.

B(C6F5)3-Catalyzed Hydroarylation of Terminal Alkynes with Phenols

We developed a B(C6F5)3 catalyzed hydroarylation of terminal alkynes with various phenols at room temperature without adding any additives, leading to the synthesis of 2-gem-vinylphenols with good regio-selectivity. Those transformations featured a broad substrate scope with moderate yields. Mechanism studies indicated that those transformations proceeded through the activation of phenol by B(C6F5)3 with subsequent protonation of alkyne/Friedel-Crafts-type reaction. (Figure presented.).

Practical, Large-Scale Preparation of Benzoxepines and Coumarins through Rhodium(III)-Catalyzed C-H Activation/Annulation Reactions

Herein we disclose the assembly of benzoxepines and coumarins from 2-alkenylphenol precursors using [Cp*RhCl2]2 as the precatalyst and alkynes or carbon monoxide as reacting partners. The preparation of benzoxepines and coumarins can be scaled up to 33 mmol using low catalyst loadings.