59649-47-7Relevant articles and documents
Magnetically recoverable silica catalysed solvent-free domino Knoevenagel-hetero-Diels-Alder reaction to access divergent chromenones
Das, Pankaj,Gogoi, Chinu,Hussain, Farhaz Liaquat,Pahari, Pallab,Suri, Mrinaly
supporting information, p. 2058 - 2062 (2020/03/27)
A three-component domino Knoevenagel-hetero-Diels-Alder (DKHDA) reaction between 1,3-dicarbonyl, aldehydes/ketones, and alkenes/alkynes leading to the divergent synthesis of chromenones, dihydrochromenones, and spirocyclic chromenones is reported. The reaction was carried out under solvent-free conditions using a magnetically separable silica (Fe3O4?SiO2) catalyst. While two component DKHDA reactions are known, this is the first example of a three component DKHDA reaction involving 1,3-dicarbonyl, ketones, and alkynes producing spirocyclic pyranone derivatives. Twenty-six different highly substituted chromenones were synthesized using this methodology. A wide substrate scope due to the multicomponent nature of the reaction, high atom economy, the use of inexpensive and non-Toxic recyclable silica as the catalyst, and solvent free reaction conditions make it an advantageous process. The catalyst was characterized using different analytical techniques such as XRD, IR, HRTEM, VSM, and TGA. Based on the earlier reports a mechanism has also been proposed.
InBr3-catalyzed annulations of cyclic 1,3-diketones with aryl propargyl alcohols: a novel synthesis of 2,4-diaryldihydropyrans
Yadav,Subba Reddy,Raghavendra Rao,Narender
experimental part, p. 3963 - 3965 (2009/10/04)
The cyclic 1,3-dicarbonyl compounds undergo smooth cyclization with aryl propargyl alcohols in the presence of 10 mol % indium tribromide in refluxing dichloroethane to produce 2,4-diarylpyran derivatives in good yields with high selectivity.
HETEROCYCLIZATION OF TRIKETONES OF THE 2-(3-OXOPROPYL)CYCLOHEXANE-1,3-DIONE SERIES
Kharchenko, V. G.,Markova, L. I.,Kazarinova, T. D.,Yudovich, L. M.
, p. 758 - 761 (2007/10/02)
Triketones of the 2-(3-oxopropyl)cyclohexane-1,3-dione series have been shown for the first time to react with boron trifluoride etherate to give the novel 5-oxo-5,6,7,8-tetrahydrochromylium fluoroborates, which in turn react with ammonia to give 5-oxo-5,
