61582-64-7Relevant articles and documents
Spin Trapping as Applied to Radicals Produced by Chemical Reaction. III. Intermediates of the Reactions of Dibenzoyl Peroxide with Diethylamine and Diphenylamine
Nishimura, Norio,Nakamura, Tatsuya,Sueishi, Yoshimi,Yamamoto, Shunzo
, p. 165 - 171 (1994)
The reactions of dibenzoyl peroxide (BPO) with diethylamine (DEA) and diphenylamine (DPA) have been studied by means of an ESR technique combined with spin-trapping.In the case of the DEA/BPO system, diethylnitroxide was formed, while for the DPA/BPO syst
Synthesis of C4-Substituted Indoles via a Catellani and C-N Bond Activation Strategy
Zhang, Bo-Sheng,Wang, Fan,Yang, Ying-Hui,Gou, Xue-Ya,Qiu, Yi-Feng,Wang, Xi-Cun,Liang, Yong-Min,Li, Yuke,Quan, Zheng-Jun
supporting information, p. 8267 - 8271 (2020/11/03)
This paper describes the case of a cross study between the C-N bond cleavage reaction field and the Catellani-Lautens reaction system. A series of highly functionalized C4-substituted indoles were synthesized using this strategy. By screening the alkyl groups of amines, the energy barrier of C-N bond cleavage reaction was reduced and the corresponding allenization products were avoided. Finally, the density functional theory calculation shows that the inert C-N bond activation reaction is not a concerted process; on the contrary, the coupling reaction first generates indole quaternary ammonium salt, and then C-N bond cleavage occurs via an SN2 process.
Copper-Catalyzed Dihydroquinolinone Synthesis from Isocyanides and O-Benzoyl Hydroxylamines
Yang, Zhen,Jiang, Kun,Chen, Ying-Chun,Wei, Ye
, p. 3725 - 3734 (2019/03/20)
A copper-catalyzed protocol has been realized for the rapid assembly of dihydroquinolinones from readily accessible isocyanides and O-benzoyl hydroxylamines. The reactions (10 mol % of CuOAc, 10 mol % of dppe, 3 equiv of PhONa, 30 °C) deliver various stru