72234-23-2

Basic information

• Product Name: 1H-1,2,4-Triazole, 3-(methylthio)-1,5-diphenyl-
• CAS NO: 72234-23-2
• Molecular Formula: C15H13N3S
• Molecular Weight: 267.354
• Mol File: 72234-23-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-1,2,4-Triazole, 3-(methylthio)-1,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,4-Triazole, 3-(methylthio)-1,5-diphenyl-(72234-23-2)
• EPA Substance Registry System: 1H-1,2,4-Triazole, 3-(methylthio)-1,5-diphenyl-(72234-23-2)

Safety Data

• Hazardous Substances Data: 72234-23-2(Hazardous Substances Data)

Upstream product

• 19382-50-4 1,5-diphenyl-1,2-dihydro-[1,2,4]triazol-3-one 
• 74-88-4 methyl iodide 
• 5055-74-3 1,5-diphenyl-1,2-dihydro-1,2,4-triazole-3-thione 
• 77-78-1 dimethyl sulfate 
• 13996-86-6 N-(Benzoyl)thiocarbamidsaeure-S-methylester 
• 532-55-8 Benzoyl isothiocyanate 
• 100-63-0 phenylhydrazine 
• 13207-53-9 N-(2-phenylhydrazine-1-carbonothioyl)benzamide 
• 21406-30-4 N-Benzoylamino-dithiokohlensaeuremethylester 
• 71141-24-7 1-benzoyl-1-phenyl thiosemicarbazide 

Downstream Products

• 99793-78-9 3-Methanesulfonyl-1,5-diphenyl-1H-[1,2,4]triazole 
• 19382-50-4 1,5-diphenyl-1,2-dihydro-[1,2,4]triazol-3-one 

Relevant articles and documents

Preparation and antiarthritic activity of new 1,5-diaryl-3-alkylthio-1H-1,2,4-triazoles and corresponding sulfoxides and sulfones

A series of 1,5-diaryl-3-alkylthio-1H-1,2,4-triazoles and corresponding sulfoxides and sulfones was synthesized and evaluated as antiinflammatory agents in the rat adjuvant induced arthritis assay.Several analogues were found to be more potent than phenyl

Reactions with N-Acylimino-dithiocarbonic-acid-diesters

Reactions of N-acylimino-dithiocarbonic-acid-S,S-diesters 1 with nucleophilic compounds present new possibilities to synthesize heterocycles.With amines 1a reacts by mono- and disubstitution, respectively, of methylthio-groups to isothioureas 2 and guanidines 3, with 1,2-binucleophilic arenes to benzoheterocycles 4, with aliphatic diamines to imidazolines 5, pyrimidines 6, diazepines 7 and the hexamethylene-diamine-derivatives 8. 1a reacts also with hydrazines to 1,2,4-triazoles 9 and with hydrazides to the thiosemicarbazones 10 or 1,3,4-oxadiazoles 11.Heterocyclisations of 1 with guanidines, thiourea, salts of thiourea and amidines give the 1,3,5-triazines 12, 14, 15 and 16.N-benzoyl-dithiocarbonic-acid-methylester -amid reacts with CH-acidic compounds to thiazoles 17.The structures of the final products are determined by i.r.-, 1H-n.m.r.-, u.v.- and mass-spectras.