73120-65-7

Basic information

• Product Name: diethyl 2-methyl-2-(4-methylbenzyl)malonate
• Synonyms: diethyl 2-methyl-2-(4-methylbenzyl)malonate
• CAS NO: 73120-65-7
• Molecular Weight: 278.348
• Mol File: 73120-65-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: diethyl 2-methyl-2-(4-methylbenzyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-methyl-2-(4-methylbenzyl)malonate(73120-65-7)
• EPA Substance Registry System: diethyl 2-methyl-2-(4-methylbenzyl)malonate(73120-65-7)

Safety Data

• Hazardous Substances Data: 73120-65-7(Hazardous Substances Data)

Upstream product

• 609-08-5 Diethyl methylmalonate 
• 589-18-4 4-Methylbenzyl alcohol 
• 104-81-4 4-Methylbenzyl bromide 
• 18424-77-6 sodium diethyl methylmalonate 
• 6619-58-5 diethyl 4-methylbenzylmalonate 

Downstream Products

• 66309-83-9 2,6-dimethylindan-1-one 
• 1012-15-3 α-methyl-β-(4-methylphenyl)propionic acid 
• 105984-59-6 methyl-(4-methyl-benzyl)-malonic acid 

Relevant articles and documents

Nickel-Catalyzed Benzylic Substitution of Benzyl Esters with Malonates as a Soft Carbon Nucleophile

The nickel-catalyzed benzylic substitution of benzyl alcohol derivatives with a soft carbon nucleophile is extremely rare compared to that with a hard carbon nucleophile. We have achieved the nickel-catalyzed benzylic substitution of benzyl esters with malonates as a soft carbon nucleophile. Primary and secondary benzyl 2,3,4,5,6-pentafluorobenzoates as well as a wide variety of malonate derivatives were well tolerated in the nickel-catalyzed reaction, providing the corresponding alkylation products in 46-86% yields (34 examples). Additionally, we propose a possible reaction mechanism that would undergo via the ??1- A nd ??3-benzylnickel intermediates.

Carbon-13 Nuclear Magnetic Resonance Spectra of Pterosin-Sesquiterpenes and Related Indan-1-one Derivatives

Methyl derivatives of indan-1-one were prepared as models to aid in interpreting the carbon-13 nuclear magnetic resonance ((13)C-NMR) spectra of pterosin-sesquiterpenes which were isolated from bracken fern, Pteridium aquilinum var. latiusculum.The chemical shifts of the carbons of the methylindan-1-ones were assigned by the proton decoupling technique.All the (13)C-NMR signals of the pterosin-sesquiterpenes were assigned by means of selective proton decouplings, and from the (13)C-(1)H long-range couplings and (13)C chemical shifts of the model compounds.Keywords - indan-1-one derivative; methylindan-1-one; pterosin-sesquiterpene; methylindan-1-one synthesis; (1)H-NMR; (13)C-NMR; selective decoupling; C-H decoupling