7383-90-6

Basic information

• Product Name: 3,4'-dimethyl-1,1'-biphenyl
• Synonyms: 3,4'-dimethyl-1,1'-biphenyl;3,4'-Bitolyl
• CAS NO: 7383-90-6
• Molecular Formula: C₁₄H₁₄
• Molecular Weight: 182.26096
• EINECS: 230-958-7
• Mol File: 7383-90-6.mol
• Article Data: 68

Chemical Properties

• Melting Point: 15°C
• Boiling Point: 295.85°C
• Flash Point: 125.8 °C
• Appearance: /
• Density: 0.9940
• Refractive Index: 1.5946
• CAS DataBase Reference: 3,4'-dimethyl-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4'-dimethyl-1,1'-biphenyl(7383-90-6)
• EPA Substance Registry System: 3,4'-dimethyl-1,1'-biphenyl(7383-90-6)

Safety Data

• Hazardous Substances Data: 7383-90-6(Hazardous Substances Data)

Usage

General Description

3,4'-dimethyl-1,1'-biphenyl is a chemical compound with the molecular formula C14H14. It is a type of biphenyl, which is an organic compound consisting of two benzene rings linked together. The presence of two methyl groups at the 3 and 4' positions of the biphenyl structure gives this compound its name. 3,4'-dimethyl-1,1'-biphenyl is used in various industrial applications, including as a component in the production of polymers and plastics. It is also used in the synthesis of organic chemicals and as a research tool in the study of chemical reactions and materials science. The chemical is known to be stable under normal conditions and has low solubility in water, making it suitable for certain manufacturing processes. However, it also poses health risks if not handled properly and should be used with caution.

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Downstream Products

• 92152-01-7 biphenyl-3,4′-dicarboxylic acid 
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Relevant articles and documents

Phosphonate functionalized N-heterocyclic carbene Pd(II) complexes as efficient catalysts for Suzuki-Miyaura cross coupling reaction

A N-heterocyclic carbene (NHC) ligand, L1 bearing a pendant phosphonate ester group is used to prepare two new NHC-Pd(II) complexes, [Pd(L1)2I2] (1) and [Pd(L1)(py)I2] (2) (py = pyridine). Hydrolysis of phosphonate ester group in 2 results another Pd(II)-NHC complex, [Pd(L2)(py)I2] (3) where a phosphonic acid group is attached to the NHC ligand L2. All the three complexes are characterized by analytical and spectroscopic studies while the molecular structures of 1-2 are also determined by single crystal X-ray diffraction measurement. The catalytic efficacies of 1-3 in Suzuki-Miyaura cross coupling reactions of aryl halides and aryl boronic acid are investigated. DFT calculations were performed to decipher the role phosphonate ester or phosphonic acid substituents on the catalytic efficacy.

Preparation of metal-immobilized methacrylate-based monolithic columns for flow-through cross-coupling reactions

With the aim of developing efficient flow-through microreactors for high-throughput organic synthesis, in this work, microreactors were fabricated by chemically immobilizing palladium-, nickel-, iron-, and copper-based catalysts onto ligand-modified poly(glycidyl methacrylate-co-ethylene dimethacrylate) [poly(GMA-co-EDMA)] monoliths, which were prepared inside a silicosteel tubing (10 cm long with an inner diameter of 1.0 mm) and modified with several ligands including 5-amino-1,10-phenanthroline (APHEN), iminodiacetic acid (IDA), and iminodimethyl phosphonic acid (IDP). The performance of the resulting microreactors in Suzuki?Miyaura cross-coupling reactions was evaluated, finding that the poly(GMA-co-EDMA) monolith chemically modified with 5-amino-1,10-phenanthroline as a binding site for the palladium catalyst provided an excellent flow-through performance, enabling highly efficient and rapid reactions with high product yields. Moreover, this monolithic microreactor maintained its good activity and efficiency during prolonged use.

Direct suzuki-miyaura coupling with naphthalene-1,8-diaminato (dan)-substituted organoborons

The actually direct Suzuki-Miyaura coupling with "protected" R-B(dan) (dan = naphthalene-1,8-diaminato) was demonstrated to smoothly occur without in situ deprotection of the B(dan) moiety. The use of t-BuOK (Ba(OH)2 in some cases) as a base under anhydrous conditions is the key to the successful cross-coupling, where R-B(dan) is readily converted into a transmetalation-active borate-form, regardless of the well-accepted diminished boron-Lewis acidity.