74532-94-8

Basic information

• Product Name: 1-bromo-4-(but-1-en-1-yl)benzene
• Synonyms: 1-bromo-4-(but-1-en-1-yl)benzene
• CAS NO: 74532-94-8
• Molecular Weight: 211.101
• Mol File: 74532-94-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-bromo-4-(but-1-en-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-4-(but-1-en-1-yl)benzene(74532-94-8)
• EPA Substance Registry System: 1-bromo-4-(but-1-en-1-yl)benzene(74532-94-8)

Safety Data

• Hazardous Substances Data: 74532-94-8(Hazardous Substances Data)

Upstream product

• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 41492-05-1 p-bromobutylbenzene 
• 1122-91-4 4-bromo-benzaldehyde 
• 22135-53-1 1-(4'-bromophenyl)-1-butanol 

Downstream Products

• 75906-36-4 4-(p-bromophenyl)-butan-1-ol 
• 98453-57-7 4-(4-bromophenyl)butanoic acid methyl ester 
• 35656-89-4 4-(4-bromophenyl)butanoic acid 

Relevant articles and documents

Ruthenium-Catalyzed Dehydrogenation Through an Intermolecular Hydrogen Atom Transfer Mechanism

The direct dehydrogenation of alkanes is among the most efficient ways to access valuable alkene products. Although several catalysts have been designed to promote this transformation, they have unfortunately found limited applications in fine chemical synthesis. Here, we report a conceptually novel strategy for the catalytic, intermolecular dehydrogenation of alkanes using a ruthenium catalyst. The combination of a redox-active ligand and a sterically hindered aryl radical intermediate has unleashed this novel strategy. Importantly, mechanistic investigations have been performed to provide a conceptual framework for the further development of this new catalytic dehydrogenation system.

Iron catalyzed methylation and ethylation of vinyl arenes

Short alkyl chain Heck (type) reactions, especially methyl Heck reactions, are a difficult aspect of the alkyl Heck reaction. To provide a solution to this problem, iron-catalyzed methyl, ethyl and propyl Heck reactions were developed using readily available alkyl peroxides as alkyl sources. The reaction conditions were mild, clean, and easy to handle. No additive was needed, and no hazardous waste was generated. The products were obtained in up to 99% yield of one isomer for most situations. This reaction works for many types of olefin and tolerates a variety of functional groups. Several late-stage functionalizations of natural products and drug molecules were conducted to demonstrate the synthetic applications of this reaction.