7461-75-8Relevant articles and documents
Compositions for prevention/prophylactic treatment of poison ivy dermatitis
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Page/Page column 18-20, (2016/09/12)
The present invention, in one or more embodiments, comprises water-soluble derivatives of 3-n-pentadecylcatechol (poison ivy urushiol saturated congener) and/or 3-n-heptadecylcatechol (poison oak urushiol saturated congener) as compositions for the prevention and/or prophylactic treatment of contact dermatitis caused by poison ivy and poison oak. The present invention is also directed towards processes for making such compounds. Disclosed are compounds which are effective for tolerizing and desensitizing a subject against allergens contained in plants of the Anacardiaceae and Ginkgoaceae families comprising water soluble urushiol esters of general formula (I) tolerizing and desensitizing mammals, including humans, to allergens contained in plants of the Anacardiaceae and Ginkgoaceae families is attained by administering a composition containing at least one water soluble urushiol ester compound.
LONG CHAIN PHENOLS FROM THE BURMESE LAC TREE, MELANORRHOEA USITATE
Du, Yumin,Oshima, Ryuichi,Yamauchi, Yoshio,Kumanotani, Ju,Miyakoshi, Tetsuo
, p. 2211 - 2218 (2007/10/02)
Key Word Index - Melanorrhoea usitate; Anacardiaceae; lac tree; sap; composition; long-chain phenols. Twenty eight constituents of the sap of the Burmese lac tree, Melanorrhoea usitate have been identified.The sap consist of homologues of thitsiol (ca 20
Long-chain Phenols. Part 18. Conversion of Anacardic Acid into Urushiol
Kiong, Lam Soot,Tyman, John H. P.
, p. 1942 - 1952 (2007/10/02)
(15:0)-Anacardic acid (6-pentadecylsalicylic acid), prepared by reduction of unsaturated anacardic acid from Anacardium occidentale, has been converted into anacardic alcohol (6-pentadecylsalicylic alcohol) and thence by oxidation at carbon into anacardaldehyde.Phenolic oxidation of anacardic alcohol led to 8-pentadecyl-1-oxaspiroocta-5,7-dien-4-one, itself readily convertible photochemically, but less so thermally, into anacardaldehyde.Reaction of thionyl chloride with anacardic acid led mainly to the anhydride, which by hydride reduction gave anacardaldehyde less satisfactorily.Dakin oxidation of anacardaldehyde furnished (15:0)-urushiol (3-pentadecylcatechol) identical chemically and from argentation t.l.c. with the hydrogenated natural product from Rhus vernicifera. (15:0)-Cardanol (3-pentadecylphenol) has been detected in hydrogenated urushiol.The composition of the unsaturated constituents of urushiol from Rhus vernicifera and Rhus toxicodendron and its mode of formation have been discussed.An improved synthesis of (15:0)-urushiol has been devised based on an organo-lithium route.Aromatic methyl ether and ester formation in this series is greatly facilitated by phase-transfer catalysis.