7466-46-8

Basic information

• Product Name: 2,3-Diphenyl-6-aminoquinoxaline
• Synonyms: 2,3-Diphenyl-6-aminoquinoxaline;6-Amino-2,3-diphenylquinoxaline
• CAS NO: 7466-46-8
• Molecular Formula: C₂₀H₁₅N₃
• Molecular Weight: 0
• Mol File: 7466-46-8.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 473.9°C at 760 mmHg
• Flash Point: 271.8°C
• Appearance: /
• Density: 1.224g/cm³
• Vapor Pressure: 3.77E-09mmHg at 25°C
• Refractive Index: 1.698
• CAS DataBase Reference: 2,3-Diphenyl-6-aminoquinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Diphenyl-6-aminoquinoxaline(7466-46-8)
• EPA Substance Registry System: 2,3-Diphenyl-6-aminoquinoxaline(7466-46-8)

Safety Data

• Hazardous Substances Data: 7466-46-8(Hazardous Substances Data)

Usage

General Description

2,3-Diphenyl-6-aminoquinoxaline is a chemical compound with the molecular formula C18H13N3. It is a yellow crystalline solid that is insoluble in water but soluble in organic solvents. 2,3-Diphenyl-6-aminoquinoxaline is used in organic synthesis as a building block for the preparation of various molecules and pharmaceuticals. It is also used in research as a fluorescent dye and a photoreactive compound. 2,3-Diphenyl-6-aminoquinoxaline has potential applications in the fields of medicine, materials science, and chemical synthesis due to its unique structure and properties.

InChI:InChI=1/C20H15N3/c21-16-11-12-17-18(13-16)23-20(15-9-5-2-6-10-15)19(22-17)14-7-3-1-4-8-14/h1-13H,21H2

Upstream product

• 7647-01-0 hydrogenchloride 
• 7466-45-7 6-nitro-2,3-diphenylquinoxaline 
• 134-81-6 benzil 
• 97-02-9 2,4-Dinitroanilin 
• 99-56-9 4-Nitrophenylene-1,2-diamine 
• 615-71-4 benzene-1,2,4-triamine 
• 64-17-5 ethanol 

Downstream Products

• 1379597-25-7 1-(4-chlorophenyl)-3-(2,3-diphenylquinoxalin-6-yl)urea 

Relevant articles and documents

Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy

Genetic models validated Inhibitor of nuclear factor (NF) kappa B kinase beta (IKKβ) as a therapeutic target for KRAS mutation associated pancreatic cancer. Phosphorylation of the activation loop serine residues (S177, S181) in IKKβ

Design, synthesis and biological evaluation of novel fluorinated heterocyclic hybrid molecules based on triazole & quinoxaline scaffolds lead to highly potent antimalarials and antibacterials

A series of novel fluorinated heterocyclic hybrid molecules based on triazole & quinoxaline scaffold were designed, synthesized and evaluated for inhibition of Plasmodium falciparum, a virulent human malaria parasite. Mono and bis triazole tagged quinoxal

A new facile, efficient synthesis and structure peculiarity of quinoxaline derivatives with two benzimidazole fragments

A highly efficient and versatile method for the synthesis of quinoxaline derivatives with two benzimidazole fragments have been developed on the basis of the ring contraction of 3-(benzimidazo-2-yl)quinoxalin-2(1H)-one with 1,2-diaminobenzene and its various types of substituted and condensed derivatives. Owing to the inter- and intramolecular processes, involving self association, proton exchange, conformational, and/or tautomeric exchanges between several forms for most of the bis-benzimidazolylquinoxalines signals of bridged and neighboring carbon atoms and the hydrogen atoms of the neighboring carbon atoms of benzimidazole fragments in the NMR spectra are broadened. The conjugation between the benzimidazole fragments and the quinoxaline core of the molecules is increased from the quinoxaline derivative (10c) to its thiadiazol[f]- (17) and pyrrolo[a]-(19) annulated derivatives, resulting in a greater planarity of the molecule as a whole.