79560-16-0

Basic information

• Product Name: Butanedioic acid, [(3,4-dichlorophenyl)phenylmethylene]-, 1-ethyl ester
• CAS NO: 79560-16-0
• Molecular Formula: C19H16Cl2O4
• Molecular Weight: 379.24
• Mol File: 79560-16-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butanedioic acid, [(3,4-dichlorophenyl)phenylmethylene]-, 1-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanedioic acid, [(3,4-dichlorophenyl)phenylmethylene]-, 1-ethyl ester(79560-16-0)
• EPA Substance Registry System: Butanedioic acid, [(3,4-dichlorophenyl)phenylmethylene]-, 1-ethyl ester(79560-16-0)

Safety Data

• Hazardous Substances Data: 79560-16-0(Hazardous Substances Data)

Upstream product

• 6284-79-3 3,4-dichlorobenzophenone 
• 123-25-1 succinic acid diethyl ester 

Downstream Products

• 79836-45-6 trans-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine 
• 79617-95-1 cis-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthaleneamine 
• 79617-96-2 Sertraline 
• 79951-46-5 trans-(1R,4S)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine 
• 91797-60-3 trans-(1S,4R)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine 
• 79617-98-4 (1R,4R)-sertraline 
• 79560-20-6 N-[4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene]methanamine 
• 149620-65-5 4-(3,4-dichlorophenyl)-4-phenylbutyric acid 
• 79560-18-2 4-(3,4-dichlorophenyl)-4-phenylbutanoic acid 
• 79560-19-3 4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one 
• 79560-17-1 4-(3,4-dichlorophenyl)-4-phenylbut-3-enoic acid 

Relevant articles and documents

Nontricyclic Antidepressant Agents Derived from cis- and trans-1-Amino-4-aryltetralins

The need for drugs that lack the obtrusive and limiting side effects of the tricyclic antidepressants has prompted the search for agents with greatly enhanced selectivity for specific mechanisms believed to be essential for antidepressant efficacy.The potential role of derangements of 5-HT pathways in the etiology of depression has long been suspected and has given impetus to the development of newer compounds that accentuate inhibition of serotonin reuptake.This paper presents structure-activity relationship for a series of cis-1-amino-4-(substituted-aryl)tetralins, which are surprisingly potent and selective inhibitors of serotonin uptake in in vitro models.These compounds are pharmacologically distinct from corresponding members of the trans series, which also potently block uptake of dopamine and norepinephrine.The activity in both cis and trans series is stereospecific, being restricted to the cis-(1S,4S) and the trans-(1R,4S) enantiomers.