79667-91-7 Usage
Description
2,2-Difluoroethylamine hydrochloride is a fluorinated aliphatic amine compound that serves as a versatile building block in the synthesis of various pharmaceutical compounds, particularly those with anti-tumor properties.
Uses
Used in Pharmaceutical Industry:
2,2-Difluoroethylamine hydrochloride is used as a key intermediate for the preparation of a wide range of pharmaceutical compounds, including anti-tumor agents, due to its unique fluorinated structure and reactivity.
Used in Organic Chemistry:
2,2-Difluoroethylamine hydrochloride is used as a precursor for the synthesis of difluoromethyl diazomethane species (CF2HCHN2), an elusive and highly reactive intermediate. This intermediate can be generated in situ in the presence of tert-butyl nitrite and a catalytic amount of acetic acid, enabling the development of novel chemical reactions and applications in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 79667-91-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,6,6 and 7 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 79667-91:
(7*7)+(6*9)+(5*6)+(4*6)+(3*7)+(2*9)+(1*1)=197
197 % 10 = 7
So 79667-91-7 is a valid CAS Registry Number.
79667-91-7Relevant articles and documents
PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE
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Page/Page column 6, (2012/07/31)
A process for the preparation of 2,2-difluoroethylamine, comprising the reaction of 2,2-difluoro-1-chloroethane with an imide of the formula (II) in the presence of an acid scavenger, to give a compound of the formula (III) in which, in the compounds of the formulae (II) and (III), R1 and R2 are, each independently of one another, hydrogen or C1-C6-alkyl or R1 and R2 form, together with the carbon atoms to which they are bonded, a six-membered aromatic ring which is optionally substituted; and the cleavage of 2,2-difluoroethylamine by reaction of the compound of the formula (III) with acid, base or hydrazine.
PROCESS FOR PREPARING 2,2-DIFLUOROETHYLAMINE AND SALTS THEREOF PROCEEDING FROM DIFLUOROACETONITRILE
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Page/Page column 3, (2011/07/29)
The present invention relates to a process for preparing 2,2-difluoroethylamine of the formula (I) and salts thereof, for example sulphates, hydrochlorides or acetates, which proceeds from difluoroacetonitrile.