82323-82-8Relevant articles and documents
Dual C(sp3)-H Functionalization of Cyclic Ethers via Singlet Oxygen-Mediated Ring Opening and Ring Closing
Yuan, Xu,Yu, Xianglin,He, Kun,Zhang, Ruihan,Xiao, Weilie,Lin, Jun,Zhan, Zhajun,Cheng, Xiaohong,Shao, Zhihui,Jin, Yi
supporting information, p. 8267 - 8272 (2021/10/25)
A metal-free dual C(sp3)-H bond functionalization of saturated cyclic ethers via photooxidative singlet oxygen-mediated ring opening and ring closing has been developed, providing a method for generating hydrobenzofurans/pyrans/dioxins. Mechanistic studies have confirmed that ring-opening intermediates were effectively generated by singlet oxygen-mediated C(sp3)-H activation and efficiently reacted with aldehydes and activated methylene compounds to form a wide array of products with high diastereoselectivities (up to >95:5 dr). This study is a rare example of α,β-dual C(sp3)-H bond functionalization of ethers.
In Situ Generated Magnesium Cyanide as an Efficient Reagent for Nucleophilic Cyanation of Nitrosoalkenes and Parent Nitronates
Ushakov, Pavel Yu.,Tabolin, Andrey A.,Ioffe, Sema L.,Sukhorukov, Alexey Yu.
supporting information, p. 1888 - 1892 (2019/01/30)
In situ generated magnesium cyanide [NaCN/Mg(ClO4)2] is suggested as a convenient, readily available, non-volatile and organic-soluble reagent for hydrocyanation reactions. It was successfully used for nucleophilic cyanation of nitrosoalkenes, nitronates, as well as other typical π-electrophiles, such as imines, α,β-unsaturated ketones, alkylidenemalonates and azoalkenes.
Synthesis of β-Cyano Ketones Promoted by a Heterogeneous Fluoride Catalyst
Strappaveccia, Giacomo,Angelini, Tommaso,Bianchi, Luca,Santoro, Stefano,Piermatti, Oriana,Lanari, Daniela,Vaccaro, Luigi
, p. 2134 - 2139 (2016/07/16)
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