883726-88-3

Basic information

• Product Name: 2,3-diMethyl-2-(triMethylsilyloxy)butanenitrile
• Synonyms: 2,3-diMethyl-2-(triMethylsilyloxy)butanenitrile
• CAS NO: 883726-88-3
• Molecular Formula: C9H19NOSi
• Molecular Weight: 185
• Mol File: 883726-88-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,3-diMethyl-2-(triMethylsilyloxy)butanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-diMethyl-2-(triMethylsilyloxy)butanenitrile(883726-88-3)
• EPA Substance Registry System: 2,3-diMethyl-2-(triMethylsilyloxy)butanenitrile(883726-88-3)

Safety Data

• Hazardous Substances Data: 883726-88-3(Hazardous Substances Data)

Usage

General Description

2,3-diMethyl-2-(triMethylsilyloxy)butanenitrile is a chemical compound with the molecular formula C9H19NO. It is a nitrile compound that consists of a butanenitrile core with two methyl groups attached to the second and third carbon atoms, as well as a triMethylsilyloxy group attached to the second carbon atom. 2,3-diMethyl-2-(triMethylsilyloxy)butanenitrile is commonly used as a reagent in organic synthesis reactions, particularly in the preparation of various chemical compounds. It is also used in the production of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it is known for its ability to act as a versatile building block in the synthesis of complex organic molecules.

Upstream product

• 563-80-4 3-methyl-butan-2-one 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 4111-10-8 (+/-)-2-hydroxy-2,3-dimethylbutanenitrile 
• 92735-50-7 (R)-(-)-2-hydroxy-2,3-dimethylbutanoic acid 
• 78640-99-0 (S)-(+)-2-hydroxy-2,3-dimethylbutanoic acid 
• 99563-93-6 4-amino-5-isopropyl-5-methyl-2(5H)-furanone 

Relevant articles and documents

n-Butyllithium as a highly efficient precatalyst for cyanosilylation of aldehydes and ketones

A highly efficient cyanosilylation protocol mediated by the easily availablen-BuLi with a wide range of aldehydes and ketones was developed. This protocol features excellent yields with very lown-BuLi loadings (0.01-0.05 mol%) at room temperature, solvent

Syntheses, Structures, and Catalytic Activities of the Anionic Heterobimetallic Rare-Earth Metal Complexes Supported by Pyrrolyl-Substituted 1,2-Diimino Ligands

A series of the anionic heterobimetallic rare-earth metal complexes supported by trans- or chiral pyrrolyl-substituted 1,2-diimino ligands were synthesized in good yields via reactions of [(Me3Si)2N]3RE(μ-Cl)Li(THF)3

A cationic aluminium complex: An efficient mononuclear main-group catalyst for the cyanosilylation of carbonyl compounds

A structurally characterized cationic aluminium complex [(AT)Al(DMAP)]+[OTf]- (3) stabilized through a relatively nonbulky aminotroponate (AT) ligand is reported (DMAP = 4-(dimethylamino)pyridine). This compound was found to work as