9004-95-9 Usage
Description
Polyethylene Glycol Monocetyl Ether(Cetomacrogol 1000) is off-white waxy solid. Polyethylene Glycol Monocetyl Ether is the tradename for polyethylene glycol hexadecyl ether , which is nonionic surfactant produced by the ethoxylation of cetyl alcohol to give a material with the general formula HO(C2H4O)nC16H33. Several grades of this material are available depending of the level of ethoxylation performed, with repeat units (n) of polyethylene glycol varying between 2 and 20. Commercially it can be known as Brij 58 (when n=20) or Brij 56 (when n=10).
Uses
Different sources of media describe the Uses of 9004-95-9 differently. You can refer to the following data:
1. Polyethylene glycol hexadecyl ether is used as a surface active agent in cosmetics. Polyethylene glycol hexadecyl ether is a compound of derivatives of cetyl, lauryl, stearyl, and oleyl alcohols mixed with ethylene oxide.Non-ionic surfactant of the polyethylene glycol family. Polyethylene glycol hexadecyl ether is used as a solubilizer and emulsifying agent in foods, cosmetics, and pharmaceuticals, often as an ointment base, and also as a research tool.?Polyethylene glycol hexadecyl ether is used as an oil in water (O/W) emulsifier for creams/lotions, and a wetting agent.
2. Polyethylene glycol hexadecyl ether, or Brij 58, has been used in a study to assess properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons. It has also been used in a study to investigate RNase-sensitive constraint of bacterial nucleoid structure.
3. ceteth is used as a surface active agent in cosmetics. It is a compound of derivatives of cetyl, lauryl, stearyl, and oleyl alcohols mixed with ethylene oxide.
4. Brij? C10 is a surfactant that can be used for applications such as: improving the wetting of PEDOT:PSS which can further be used in the fabrication of thin film transistors, formation of reverse micelles for the synthesis of high yielding nanostructures, in the preparation of platinum electrode for fuel cell applications
General Description
Brij 58 is a nonionic surfactant or detergent for protein extraction and permeabilization of cells. It may be used in the preparation of yeast spheroplasts.
Flammability and Explosibility
Nonflammable
Check Digit Verification of cas no
The CAS Registry Mumber 9004-95-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 4 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 9004-95:
(6*9)+(5*0)+(4*0)+(3*4)+(2*9)+(1*5)=89
89 % 10 = 9
So 9004-95-9 is a valid CAS Registry Number.
9004-95-9Relevant articles and documents
N4 - hydroxycytidine derivative as well as preparation method and application thereof
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Paragraph 0089-0093, (2021/09/01)
The invention relates to N4 - hydroxycytidine derivatives as shown in general formula I. A pharmaceutically acceptable salt, a tautomer thereof, a stereoisomer thereof, a metabolite thereof, a metabolic precursor thereof, or a prodrug thereof, and the substituted N4 - hydroxycytidine derivative structure of the structure of Formula I. The pharmaceutical composition is used for preparing medicaments for treating infections such as SARS-CoV, HBV, HCV, H1N1, Ebola and SARS-CoV - 2, can effectively inhibit influenza viruses and SARS-CoV - 2 viruses, and can have the same result on other RNA viruses. The series of compounds can be applied to preparation of anti RNA virus drugs. The medicine is used for preparing a medicine for treating virus infection and is used for preparing a vaccine adjuvant for treating virus infection.
An N4-hydroxycytoside derivative and its preparation method and use
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Paragraph 0080-0084, (2021/12/07)
The present invention provides an N4- hydroxycytidine derivative as shown in formula I, a pharmaceutically acceptable salt thereof, a tautomer thereof, a stereoisomer thereof, a metabolite thereof, a metabolic precursor thereof, or a prodrug thereof: 。 The compounds of the present invention have the following significant advantages: (1) the N4-hydroxycytidine compounds and their derivatives have a highly efficient inhibitory activity of RNA-dependent RNA polymerases of RNA viruses; (2) the N4-hydroxycytoside compounds and their derivatives and pharmaceutical compositions are widely used, can be prepared to treat / prevent SARS-CoV, HBV, HCV, H1N1, Ebola or SARS-CoV-2 virus infection disease drugs.
Liposome Enhanced Detection of Amyloid Protein Aggregates
Kocsis, Istvan,Sanna, Elena,Hunter, Christopher A.
, p. 647 - 650 (2021/02/06)
Thioflavin-T is used to image amyloid aggregates because of the excellent turn-on fluorescence properties, but binding affinities are low. By mounting multiple dye units on the surface of a vesicle, the binding affinity for α-synuclein fibrils is increased by three orders of magnitude, and the optical response is increased. Cooperative interactions of the dye headgroup and lipid with the protein provide a general strategy for the construction of multivalent amyloid probes based on vesicles.
