912469-48-8

Basic information

• Product Name: [3-methoxy-2-(2-trimethylsilylethynyl)phenyl]methanol
• Synonyms: [3-methoxy-2-(2-trimethylsilylethynyl)phenyl]methanol
• CAS NO: 912469-48-8
• Molecular Weight: 234.37
• Mol File: 912469-48-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [3-methoxy-2-(2-trimethylsilylethynyl)phenyl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [3-methoxy-2-(2-trimethylsilylethynyl)phenyl]methanol(912469-48-8)
• EPA Substance Registry System: [3-methoxy-2-(2-trimethylsilylethynyl)phenyl]methanol(912469-48-8)

Safety Data

• Hazardous Substances Data: 912469-48-8(Hazardous Substances Data)

Upstream product

• 137898-13-6 2-trifluoromethylsulphonyloxy-3-methoxybenzaldehyde 
• 1066-54-2 trimethylsilylacetylene 
• 132338-45-5 methyl 3-methoxyl-2-(trifluoromethylsulfonyloxy)benzoate 
• 6342-70-7 3-methoxymethylsalicylate 
• 912469-32-0 3-methoxy-2-trimethylsilanylethynyl-benzoic acid methyl ester 

Downstream Products

• 912469-49-9 3-methoxy-2-((trimethylsilyl)ethynyl)benzaldehyde 
• 1373444-00-8 2-(3-butynyl)-1-{[2-(3-butynyl)-6-methoxyphenyl]ethynyl}naphthalene 
• 912469-44-4 3-[2-(2-[1,3]dioxan-2-yl-6-methoxy-phenyl)-4,5-dimethoxy-naphthalen-1-yloxy]-propan-1-ol 
• 912469-52-4 C₂₅H₂₆O₇ 
• 912469-51-3 acetic acid 2-(2-[1,3]dioxan-2-yl-6-methoxy-phenyl)-4,5-dimethoxy-naphthalen-1-yl ester 
• 912469-38-6 7-(2-[1,3]dioxan-2-yl-6-methoxy-phenylethynyl)-5,8,8-trimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-ol 
• 912469-37-5 2-(2-[1,3]dioxan-2-yl-6-methoxy-phenyl)-4,5-dimethoxy-naphthalen-1-ol 
• 912469-42-2 2-(1-acetoxy-4,5-dimethoxy-naphthalen-2-yl)-3-methoxy-benzoic acid methyl ester 
• 912469-41-1 acetic acid 2-(2-formyl-6-methoxy-phenyl)-4,5-dimethoxy-naphthalen-1-yl ester 
• 912469-35-3 2-(2-ethynyl-3-methoxy-phenyl)-[1,3]dioxane 
• 912469-50-2 2-ethynyl-3-methoxybenzaldehyde 

Relevant articles and documents

Nickel-Catalyzed Construction of Chiral 1-[6]Helicenols and Application in the Synthesis of [6]Helicene-Based Phosphinite Ligands

Two 1-[6]helicenol derivatives were synthesized by Ni-catalyzed [2+2+2] cycloaddition on a multigram scale. Both enantiomers of the 1-[6]helicenols could be efficiently prepared by simple optical resolution. As a synthetic application of helically chiral 1-[6]helicenols, a novel class of [6]helicene-based phosphinites was developed; these compounds represent the first examples of helically chiral phosphinite ligands. Up to 90 % ee was obtained for the Pd-catalyzed asymmetric allylic alkylation reaction.