95-59-0

Basic information

• Product Name: 2,3-DICHLORO-P-DIOXANE
• Synonyms: 2,3-Dichloro-1,4-dioxane;2,3-dichloro-4-dioxane;2,5-dichloro-p-dioxane;p-Dioxane, 2,3-dichloro-;2,3-DICHLORO-P-DIOXANE;NISTC95590;2,3-DICHLORO-PARA-DIOXANE
• CAS NO: 95-59-0
• Molecular Formula: C₄H₆Cl₂O₂
• Molecular Weight: 156.99524
• EINECS: 202-435-3
• Mol File: 95-59-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 30°C
• Boiling Point: 218.43°C (rough estimate)
• Flash Point: 93.9 °C
• Appearance: /
• Density: 1.4680
• Vapor Pressure: 0.209mmHg at 25°C
• Refractive Index: 1.4928 (estimate)
• CAS DataBase Reference: 2,3-DICHLORO-P-DIOXANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DICHLORO-P-DIOXANE(95-59-0)
• EPA Substance Registry System: 2,3-DICHLORO-P-DIOXANE(95-59-0)

Safety Data

• Hazardous Substances Data: 95-59-0(Hazardous Substances Data)

Usage

Uses

2,3-Dichloro-1,4-dioxane is an intermediate in the synthesis of 4-(2-Aminophenyl)-3-morpholinone (A625985). 4-(2-Aminophenyl)-3-morpholinone is a reagent used in the preparation of various Morpholine based pharmaceuticals.

InChI:InChI=1/C4H6Cl2O2/c5-3-4(6)8-2-1-7-3/h3-4H,1-2H2

Upstream product

• 56-23-5 tetrachloromethane 
• 543-75-9 1,4-dioxene 
• 7782-50-5 chlorine 
• 123-91-1 1,4-dioxane 
• 7446-70-0 aluminium trichloride 
• 3883-42-9 cis-2,3-dichloro-1,4-dioxane 
• 71-43-2 benzene 
• 7719-09-7 thionyl chloride 
• 95-59-0 trans-2,3-dichloro-1,4-dioxane 

Downstream Products

• 854388-33-3 2,3-bis-(4-nitro-phenoxy)-[1,4]dioxane 
• 131543-46-9 Glyoxal 
• 107-21-1 ethylene glycol 
• 4336-10-1 cis-2,3-diphenyl-[1,4]dioxane 
• 4336-10-1 (+/-)-trans-2,3-diphenyl-[1,4]dioxane 
• 16088-56-5 cis-2,3-bis-diethoxythiophosphorylmercapto-[1,4]dioxane 
• 78-34-2 (+/-)-trans-2,3-bis-diethoxythiophosphorylmercapto-[1,4]dioxane 
• 7504-91-8 2,3-Bis-<4-chlor-phenyl>-1,4-dioxan 
• 138609-88-8 1,1,2,2-tetrakis(benzylthio)etane 
• 35030-10-5 (+/-)-2r,3t-bis-(4-methoxy-phenyl)-[1,4]dioxane 
• 72701-41-8 2,3-diphenoxy-[1,4]dioxane 
• 95-59-0 (-)-2r,3t-dichloro-[1,4]dioxane 
• 50695-44-8 2,3,5,6-cis-anti-cis-Tetrachlorodioxan 
• 98492-48-9 2,3-Bis-<2-chlor-ethoxy>-1,4-dioxan 

Relevant articles and documents

Synthesis of isotopically labeled fusarium mycotoxin 13C 2-moniliformin [1-hydroxycyclobut-1-ene-3,4-dione]

The total synthesis of isotopically labeled [13C-1- hydroxycyclobut-1-ene-3,4-dione (moniliformin) a fungal toxic secondary metabolite to be used as internal standard for mycotoxin analysis is described. The synthesis proceeds in four steps starting from 1,4-dioxane, which was converted to 2,3-dihydro-1,4-dioxine followed by a [2+2]-cycloaddition with trichloroacetyl chloride-1,2-13Cas 13C source. The 13Clabeled cyclobutanone precursor was transformed to [ 13C-moniliformin by acid-catalyzed hydrolysis. The successful incorporation of two 13C atoms was proven by detailed NMR and mass spectrometric studies of labeled moniliformin and its precursor. Georg Thieme Verlag Stuttgart - New York.

Dialkoxyacetylenes: Di-tert-butoxyethyne, a valuable synthetic intermediate

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