957-46-0

Basic information

• Product Name: 3,4-diphenyl-5(2H)-isoxazolone
• Synonyms: 3,4-diphenyl-5(2H)-isoxazolone
• CAS NO: 957-46-0
• Molecular Formula: C₁₅H₁₁NO₂
• Molecular Weight: 237.25334
• Mol File: 957-46-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-diphenyl-5(2H)-isoxazolone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-diphenyl-5(2H)-isoxazolone(957-46-0)
• EPA Substance Registry System: 3,4-diphenyl-5(2H)-isoxazolone(957-46-0)

Safety Data

• Hazardous Substances Data: 957-46-0(Hazardous Substances Data)

Upstream product

• 32569-84-9 ethoxyethynylbenzene 
• 65-85-0 benzoic acid 
• 58929-02-5 ethyl 2,3-diphenyl-3-oxopropanoate 
• 5415-07-6 3-oxo-2,3-diphenyl-propionitrile 
• 94-41-7 benzalacetophenone 
• 140-29-4 phenylacetonitrile 
• 861777-28-8 2-bromo-4-nitro-1,3,4-triphenyl-butan-1-one 
• 96260-76-3 4-nitro-1,3,4-triphenyl-butan-1-one 
• 93-89-0 benzoic acid ethyl ester 
• 622-42-4 1-nitro-1-phenylmethane 
• 408532-96-7 (5-hydroxy-3,4-diphenyl-4,5-dihydro-isoxazol-5-yl)-phenyl ketone 
• 35061-99-5 3-Oxo-2,3-diphenyl-propionamide 
• 54108-62-2 3-Oxo-2,3-diphenylpropenoic acid methyl ester 
• 25632-76-2 5-methoxy-3,4-diphenylisoxazole 

Downstream Products

• 61760-53-0 2,3-diphenylimidazo[1,2-a]quinoline 
• 909104-02-5 2,3-diphenylimidazo[1,2-a]pyrimidine 
• 7766-00-9 2-methyl-3,4-diphenyl-2H-isoxazol-5-one 

Relevant articles and documents

One-Pot Reaction of Carboxylic Acids and Ynol Ethers for the Synthesis of β-Keto Esters

An one-pot reaction of carboxylic acids and ynol ethers for the synthesis of β-keto esters has been developed. Under promotion of Ag2O, various carboxylic acids and ynol ethers could transform to α-acyloxy enol esters, which undergo a following DMAP-catalyzed rearrangement to deliver β-keto esters rapidly. This method provides a direct approach to β-keto esters from carboxylic acids without any preactivation. The protocol features mild reaction conditions, broad substrate scope, and the products could be transformed to an array of compounds.