96619-89-5

Basic information

• Product Name: methyl 2-allyloxy-m-anisate
• Synonyms: methyl 2-allyloxy-m-anisate;3-Methoxy-2-(2-propenyloxy)benzoic acid methyl ester
• CAS NO: 96619-89-5
• Molecular Formula: C₁₂H₁₄O₄
• Molecular Weight: 222.23716
• EINECS: 306-201-2
• Mol File: 96619-89-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 315.1°Cat760mmHg
• Flash Point: 136.7°C
• Appearance: /
• Density: 1.092g/cm³
• Vapor Pressure: 0.000445mmHg at 25°C
• Refractive Index: 1.505
• CAS DataBase Reference: methyl 2-allyloxy-m-anisate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-allyloxy-m-anisate(96619-89-5)
• EPA Substance Registry System: methyl 2-allyloxy-m-anisate(96619-89-5)

Safety Data

• Hazardous Substances Data: 96619-89-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H14O4/c1-4-8-16-11-9(12(13)15-3)6-5-7-10(11)14-2/h4-7H,1,8H2,2-3H3

Upstream product

• 6342-70-7 3-methoxymethylsalicylate 
• 106-95-6 allyl bromide 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 877-22-5 3-methoxysalicylic acid 

Downstream Products

• 85614-43-3 2-hydroxy-3-methoxy-5-(2-propeny)benzoic acid, methyl ester 
• 96619-88-4 2-(allyloxy)-3-methoxybenzoic acid 
• 2216-99-1 5-allyl-2-hydroxy-3-methoxybenzoic acid 
• 579-60-2 6-allylguaicol 
• 97-53-0 4-allylguaiacol 
• 133129-41-6 N-((R)-1-Ethyl-pyrrolidin-2-ylmethyl)-5-(2-fluoro-ethyl)-2,3-dimethoxy-benzamide 
• 133129-40-5 (S)-2,3-dimethoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(2-fluoroethyl)benzamide 
• 133129-50-7 2,3-dimethoxy-5-(fluoropropyl)benzoic acid, methyl ester 
• 133129-48-3 2,3-dimethoxy-5-(3-hydroxypropyl)benzoic acid, methyl ester 
• 133129-49-4 2,3-dimethoxy-5-<3-<<(4-methylphenyl)sulfonyl>oxy>propyl>benzoic acid, methyl ester 
• 133129-53-0 2,3-Dimethoxy-5-(2-trifluoromethanesulfonyloxy-ethyl)-benzoic acid methyl ester 
• 126247-33-4 FPMP 
• 133129-45-0 (S)-2,3-dimethoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-propylbenzamide 
• 133129-51-8 2,3-dimethoxy-5-(fluoropropyl)benzoic acid 

Relevant articles and documents

Choleretic drug alibendol preparation method

The invention belongs to the field of drug synthesis, and provides an alibendol preparation method, which comprises: selecting 2-hydroxy-3-methoxybenzaldehyde as a raw material, selecting an efficientoxidative esterification catalyst, carrying out one-step oxidative esterification to obtain methyl 2-hydroxy-3-methoxybenzoate, carrying out a reaction on the methyl 2-hydroxy-3-methoxybenzoate and allyl bromide under the action of an alkali to generate methyl 2-allyloxy-3-methoxybenzoate, carrying out a para Claisen rearrangement reaction on the methyl 2-allyloxy-3-methoxybenzoate at a high temperature to obtain methyl 2-hydroxy-3-methoxy-5-allylbenzoate, and carrying out an aminolysis reaction in ethanolamine to generate alibendol. Compared with the traditional synthetic process, the new process of the present invention has characteristics of simple synthesis steps, convenient post-treatment and good product quality, and is suitable for industrial production.