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(R)-3-Hydroxypyrrolidine

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Name

(R)-3-Hydroxypyrrolidine

EINECS -0
CAS No. 2799-21-5 Density 1.065 g/cm3
PSA 32.26000 LogP -0.33060
Solubility Soluble in water and methanol. Melting Point 15 °C
Formula C4H9NO Boiling Point 224.7 °C at 760 mmHg
Molecular Weight 87.1216 Flash Point 105.8 °C
Transport Information N/A Appearance clear yellow to orange-brown viscous liquid
Safety 26-37/39 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 2799-21-5 ((R)-3-Hydroxypyrrolidine) Hazard Symbols IrritantXi
Synonyms

3-Pyrrolidinol,(R)-;(-)-3-Pyrrolidinol;(3R)-3-Hydroxypyrrolidine;(3R)-3-Pyrrolidinol;(3R)-Pyrrolidin-3-ol;(R)-(-)-3-Pyrrolidinol;(R)-3-Hydroxypyrrolidine;(R)-3-Pyrrolidinol;3-(R)-Hydroxypyrrolidine;3-(R)-Pyrrolidinol;(R)-(+)-3-Hydroxypyrrolidine;

Article Data 30

(R)-3-Hydroxypyrrolidine Specification

The IUPAC name of (R)-3-Hydroxypyrrolidine is pyrrolidin-3-ol. With the CAS registry number 2799-21-5, it is also named as 3-Pyrrolidinol, (3R)-; (R)-3-Pyrrolidinol. The product's categories are pharmacetical, API intermediates, chiral building blocks, simple alcohols (chiral) and synthetic organic chemistry. It is clear yellow to orange-brown viscous liquid which is hygroscopic and sensitive to air. So this product is stored in a tightly closed container which should be placed in a dry area. In addition, it is toxic to water.

The other characteristics of this product can be summarized as: (1)ACD/LogP: -1.20; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -4.29; (4)ACD/LogD (pH 7.4): -3.9; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 1; (11)Index of Refraction: 1.484; (12)Molar Refractivity: 23.38 cm3; (13)Molar Volume: 81.7 cm3; (14)Polarizability: 9.27×10-24 cm3; (15)Surface Tension: 35.6 dyne/cm; (16)Enthalpy of Vaporization: 53.63 kJ/mol; (17)Vapour Pressure: 0.018 mmHg at 25°C; (18)Exact Mass: 87.068414; (19)MonoIsotopic Mass: 87.068414; (20)Topological Polar Surface Area: 32.3; (21)Heavy Atom Count: 6.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you contact with skin, flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. If you inhale this chemical, remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. So people should avoid breathing dust, vapor, mist, or gas. If you want to contact this product, you must wear suitable gloves and eye/face protection.

People can use the following data to convert to the molecule structure.
1. SMILES: O[C@@H]1CCNC1;
2. InChI: InChI=1/C4H9NO/c6-4-1-2-5-3-4/h4-6H,1-3H2/t4-/m1/s1.

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