Name: 1-Testosterone
SKU: 65-06-5

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Basic Information

Molecular Structure:
CAS No.:	65-06-5
Name:	1-Testosterone

Formula:	C19H28 O2
Molecular Weight:	288.43
Synonyms:	5a-Androst-1-en-3-one, 17b-hydroxy- (8CI);1-Testosterone;17b-Hydroxy-5a-androst-1-en-3-one;5a-Androst-1-en-17b-ol-3-one;NSC 121140;NSC 39366;
EINECS:	200-533-0
Density:	1.1561
Melting Point:	75-85°C
Boiling Point:	120°C 0,5mm
Flash Point:	179.5oC
Hazard Symbols:	Xi
PSA:	37.30000
LogP:	3.73510

Synthetic route

: 64-82-4, 6656-41-3, 21507-42-6, 25615-33-2, 54631-35-5, 79732-37-9, 97413-69-9
(5α,17β)-3-oxoandrost-1-en-17-yl acetate

Conditions	Yield
With sodium hydroxide In methanol at 20℃; for 2h;	99.8%

Conditions	Yield
With sodium hydroxide for 2h; Heating;	82.6%

Conditions	Yield
With potassium hydroxide

Conditions	Yield
With manganese(IV) oxide In dichloromethane

: 63109-26-2
2-((3S,5S,8R,9S,10R,13S,14S,17S)-3,17-Dihydroxy-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-yl)-N,N-dimethyl-acetamide

Conditions	Yield
at 250℃;

Conditions	Yield
With potassium hydroxide

Conditions	Yield
Multi-step reaction with 2 steps 1: 99.6 percent / lithium bromide; lithium carbonate / dimethylformamide / 0.5 h / Heating 2: 99.8 percent / sodium hydroxide / methanol / 2 h / 20 °C View Scheme

Conditions	Yield
Multi-step reaction with 3 steps 1: 88 percent / hydrogen chloride; bromine / acetic acid / 1 h / 20 - 25 °C 2: 99.6 percent / lithium bromide; lithium carbonate / dimethylformamide / 0.5 h / Heating 3: 99.8 percent / sodium hydroxide / methanol / 2 h / 20 °C View Scheme

Conditions	Yield
Multi-step reaction with 3 steps 1: 5.1 g / Br2 / acetic acid / 3 h / Ambient temperature 2: CaCO3 / N,N-dimethyl-acetamide / 0.33 h / Heating 3: 82.6 percent / 5percent methanolic NaOH / 2 h / Heating View Scheme

Conditions	Yield
Multi-step reaction with 2 steps 1: CaCO3 / N,N-dimethyl-acetamide / 0.33 h / Heating 2: 82.6 percent / 5percent methanolic NaOH / 2 h / Heating View Scheme