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| CAS No.: | 15679-19-3 |
|---|---|
| Name: | 2-Ethoxythiazole |
| Molecular Structure: | |
|
|
|
| Formula: | C5H7NOS |
| Molecular Weight: | 129.183 |
| Synonyms: | Nizatidine intermediate |
| EINECS: | 239-760-5 |
| Density: | 1.146 g/cm3 |
| Boiling Point: | 167.9 °C at 760 mmHg |
| Flash Point: | 55.3 °C |
| Appearance: | Colorless to light yellow liquid |
| Hazard Symbols: |
Xi
|
| Risk Codes: | 10-36/37/38 |
| Safety: | 16-26 |
| Transport Information: | UN 1993 3/PG 3 |
| PSA: | 50.36000 |
| LogP: | 1.54180 |

| Conditions | Yield |
|---|---|
| In ethanol Heating; | 90% |
| In methanol for 20h; Heating; |

O-ethyl thiocarbamate


2-ethoxythiazole

2-ethoxythiazole


5-bromo-2-ethoxythiazole

| Conditions | Yield |
|---|---|
| With N-Bromosuccinimide In N,N-dimethyl-formamide at 20℃; for 3h; | 91% |

2-ethoxythiazole


methyl phosphite

| Conditions | Yield |
|---|---|
| With manganese triacetate In acetic acid at 80℃; for 3h; | 89% |

2-ethoxythiazole


N-ethoxycarbonyl-4-piperidone


ethyl 4-(2-ethoxy-1,3-thiazol-5-yl)-4-hydroxypiperidine-1-carboxylate

| Conditions | Yield |
|---|---|
| Stage #1: 2-ethoxythiazole With n-butyllithium In tetrahydrofuran at 0℃; for 0.166667h; Stage #2: N-ethoxycarbonyl-4-piperidone In tetrahydrofuran at 0 - 25℃; for 4h; | 69% |

| Conditions | Yield |
|---|---|
| With trifluoroacetic acid In dichloromethane for 4h; Reflux; stereoselective reaction; | 68% |

2-ethoxythiazole


C5H6ClNO3S2

| Conditions | Yield |
|---|---|
| Stage #1: 2-ethoxythiazole With sec.-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere; Stage #2: With sulfur dioxide In tetrahydrofuran; hexane at 20℃; for 3h; Stage #3: With N-chloro-succinimide In tetrahydrofuran; hexane at 20℃; for 1h; | 65% |

2-ethoxythiazole

A

3H-thiazol-2-one

B

4,5-dihydro-3H,3'H-[4,5']bithiazolyl-2,2'-dione

| Conditions | Yield |
|---|---|
| With hydrogenchloride |

| Conditions | Yield |
|---|---|
| at 314.2 - 405.7℃; Kinetics; |
Molecular Structure of 2-Ethoxythiazole(15679-19-3):

IUPAC Name:2-ethoxy-1,3-thiazole
Molecular Formula:C5H7NOS
Molecular Weight:129.180180 g/mol
Appearance:colorless to light yellow liquid
Density:1.146 g/cm3
Flash Point:55.3 °C
Enthalpy of Vaporization:38.77 kJ/mol
Boiling Point:167.9 °C at 760 mmHg
Vapour Pressure:2.2 mmHg at 25 °C
Water Solubility:1745 mg/L at 25 °C
Refractive index:n20/D 1.504(lit.)
EINECS:239-760-5
Synonyms of 2-Ethoxythiazole(15679-19-3):
2-ethoxy-thiazol;FEMA 3340;FEMA NUMBER 3340;2-ETHOXYTHIAZOLE;2-ETHOXYTHIAZOLE 99+%;2-ETHOXY THIAZOLE FEMA NO.3340;Thiazole, 2-ethoxy-;2-EHTOXYTHIAZOLE
Categories of 2-Ethoxythiazole(15679-19-3):
thiazole Flavor;Alphabetical Listings;E-F;Flavors and Fragrances
