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2-NITROFLUORENE

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2-NITROFLUORENE

EINECS 210-138-5
CAS No. 607-57-8 Density 1.318 g/cm3
PSA 45.82000 LogP 3.68920
Solubility Insoluble in water Melting Point 156-158 °C(lit.)
Formula C13H9NO2 Boiling Point 374.7 °C at 760 mmHg
Molecular Weight 211.22 Flash Point 185.2 °C
Transport Information UN 3077 9/PG 3 Appearance cream powder
Safety 36/37 Risk Codes 40-68
Molecular Structure Molecular Structure of 607-57-8 (2-Nitrofluorene) Hazard Symbols HarmfulXn
Synonyms

Fluorene,2-nitro- (6CI,7CI,8CI);2-Nitro-9H-fluorene;2-Nitrofluorene;NSC 5182;

Article Data 38

2-NITROFLUORENE Chemical Properties

IUPAC Name: 2-Nitrofluorene
The MF of 2-Nitrofluorene (607-57-8) is C13H9NO2.

                    
The MW of 2-Nitrofluorene (607-57-8) is 211.22.
Synonyms of 2-Nitrofluorene (607-57-8): 2-Nitrofluorene ; 9H-Fluorene, 2-nitro- ; 2-Nitro-9H-fluorene ; Fluorene, 2-nitro- ; Fluorene, 2-nitro- (8CI) 
Product Categories: Fluorene Derivatives;Fluorenes;Fluorenes & Fluorenones;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks
Form: Cream-colored solid
Index of Refraction: 1.677  
EINECS: 210-138-5
Density: 1.318 g/ml 
Flash Point: 185.2 °C 
Boiling Point: 374.7 °C
Melting Point: 156 °C
Water Solubility: Insoluble
Stability: Stable

2-NITROFLUORENE Uses

    2-Nitrofluorene (607-57-8) is used as organic synthesis intermediates.

2-NITROFLUORENE Production

Aromatic nitro compounds, such as 2-Nitrofluorene, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups. Stable under normal conditions. Protect from bases.

2-NITROFLUORENE Toxicity Data With Reference

1.    

mmo-sat 250 ng/plate

    MUREAV    Mutation Research. 143 (1985),213.
2.    

otr-hmn:lvr 80 µg/L

    BJCAAI    British Journal of Cancer. 37 (1978),873.
3.    

skn-rat TDLo:310 mg/kg/79W-I:NEO

    JNCIAM    Journal of the National Cancer Institute. 10 (1950),1201.
4.    

ipr-mus LD50:1600 mg/kg

    JJIND8    JNCI, Journal of the National Cancer Institute. 62 (1979),911.

2-NITROFLUORENE Consensus Reports

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 46 ,1989,p. 291.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 46 ,1989,p. 277.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Adequate Data IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 46 ,1989,p. 277.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

2-NITROFLUORENE Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by intraperitoneal route. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITRO COMPOUNDS of AROMATIC HYDROCARBONS.
Safety information of 2-Nitrofluorene (607-57-8):
Hazard Codes  Xn,N
Risk Statements 
40  Limited evidence of a carcinogenic effect
51/53  Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
68  Possible risk of irreversible effects
Safety Statements 
36/37  Wear suitable protective clothing and gloves
61  Avoid release to the environment. Refer to special instructions safety data sheet
RIDADR  UN 3077 9/PG 3
WGK Germany  3
RTECS  LL8225000
HS Code  29042000

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