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3-Methylsalicylic acid

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3-Methylsalicylic acid

EINECS 201-473-8
CAS No. 83-40-9 Density 1.304 g/cm3
PSA 57.53000 LogP 1.39880
Solubility 1.5 g/L (20 °C) in water Melting Point 98-100 °C(lit.)
Formula C8H8O3 Boiling Point 293.2 °C at 760 mmHg
Molecular Weight 152.15 Flash Point 145.4 °C
Transport Information UN 2811 Appearance white to slightly reddish crystalline solid
Safety 26-36/39-22 Risk Codes 22-37/38-41
Molecular Structure Molecular Structure of 83-40-9 (3-Methylsalicylic acid) Hazard Symbols HarmfulXn
Synonyms

2,3-Cresoticacid (8CI);2,3-Cresotinic acid;2-Hydroxy-3-methylbenzoic acid;2-Hydroxy-m-toluic acid;3-MS;3-Methyl-2-hydroxybenzoic acid;Cresotic acid;Cresotinic acid;Hydroxytoluic acid;NSC17561;NSC 1772;NSC 50796;o-Cresotic acid;o-Cresotinic acid;o-Homosalicylicacid;b-Cresotinic acid;

Article Data 49

3-Methylsalicylic acid Chemical Properties

Chemical Name: 3-Methylsalicylic acid
IUPAC NAME:  2-hydroxy-3-methylbenzoic acid
CAS No.: 83-40-9
EINECS: 209-447-8
RTECS: BZ4385000
RTECS Class: Drug; Mutagen
EC Class: harmful, irritant
Molecular Formula: C8H8O3
Molecular Weight: 152.15 g/mol
Density: 1.304 g/cm3
Melting Point: 98-100 °C(lit.)
Flash Point: 145.4 °C
Boiling Point: 293.2 °C at 760 mmHg
2,3-CRESOTIC ACID(83-40-9) is volatile in steam incompatible with acid chlorides, acid anhydrides, strong bases, strong oxidizing agents.Following is the structure:

                       
The chemical synonymous of 2,3-CRESOTIC ACID(83-40-9) are AKOS BBS-00003735;2-ANISIC ACID;FEMA 3943;RARECHEM AL BO 0025;O-METHYLSALICYLIC ACID;2,3-Cresotic acid;2,3-cresoticacid;2,3-Cresotinic acid.

3-Methylsalicylic acid Uses

2,3-CRESOTIC ACID(83-40-9) is a white To slightly reddish crystalline solid,its toxicity is similar to salicylic acid. it is used in manufacturing of dyes and used as intermediates for synthesisi and dye.

3-Methylsalicylic acid Production

Product Categories about 2,3-CRESOTIC ACID(83-40-9) are Intermediates of Dyes and Pigments;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Aromatics.

3-Methylsalicylic acid Toxicity Data With Reference

mouseLD50intraperitoneal345mg/kg (345mg/kg) Farmaco, Edizione Scientifica. Vol. 20, Pg. 506, 1965.
mouseLD50oral1gm/kg (1000mg/kg)BEHAVIORAL: ANALGESIAActa Pharmaceutica Suecica. Vol. 7, Pg. 289, 1970.
ratLD50oral445mg/kg (445mg/kg) Biochimica Applicata. Vol. 10, Pg. 270, 1963.

3-Methylsalicylic acid Consensus Reports

Reported in EPA TSCA Inventory.

3-Methylsalicylic acid Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and fumes.
Hazard Codes:
    Xn: Harmful
Risk Statements about 2,3-CRESOTIC ACID(83-40-9):
    R22 Harmful if swallowed.
    R41 Risk of serious damage to the eyes.
    R36/38: Irritating to eyes and skin.
Safety Statements about 2,3-CRESOTIC ACID(83-40-9):
    S22 Do not breathe dust.
    S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    S37/39: Wear suitable gloves and eye/face protection.

3-Methylsalicylic acid Specification

1. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
2. Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
3. Personal Protection: Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
4. Fire Fighting: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire, use carbon dioxide, dry chemical powder or appropriate foam.
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