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Name	4-Hydroxy-1-methyl-2(1H)-quinolone	EINECS	N/A
CAS No.	1677-46-9	Density	1.326g/cm³
PSA	42.23000	LogP	1.24410
Solubility	N/A	Melting Point	269-271 °C(lit.)
Formula	C10H9 N O2	Boiling Point	293.4°Cat760mmHg
Molecular Weight	175.187	Flash Point	131.2°C
Transport Information	N/A	Appearance	N/A
Safety	Poison by intravenous route. Mildly toxic by ingestion. An eye irritant. When heated to decomposition it emits toxic fumes of NO_x.	Risk Codes	36/37/38
Molecular Structure		Hazard Symbols
Synonyms	Carbostyril,4-hydroxy-1-methyl- (6CI,7CI,8CI);1-Methyl-2-oxo-1,2-dihydro-4-hydroxyquinoline; 1-Methyl-4-hydroxy-2(1H)-quinolinone;1-Methyl-4-hydroxy-2-quinolone; 1-Methyl-4-hydroxycarbostyril;4-Hydroxy-1-methyl-2(1H)-quinolone; 4-Hydroxy-1-methyl-2-quinolinone;4-Hydroxy-1-methyl-2-quinolone; 4-Hydroxy-1-methylcarbostyril;4-Hydroxy-1-methylquinolin-2(1H)-one; 4-Hydroxy-1-methylquinoline-2(1H)-one;4-Hydroxy-N-methyl-2-quinolinone; 4-Hydroxy-N-methyl-2-quinolone;4-Hydroxy-N-methylcarbostyril; N-Methyl-4-hydroxyquinol-2-one; NSC 39973	Article Data	44

4-Hydroxy-1-methyl-2(1H)-quinolone Chemical Properties

IUPAC Name: 2-Hydroxy-1-methylquinolin-4-one
Synonyms of 4-Hydroxy-1-methyl-2(1H)-quinolone (CAS NO.1677-46-9): 1-Methyl-4-hydroxy-2-chinolinon ; 1-Methyl-4-hydroxy-2-chinolon ; 1-Methyl-4-hydroxycarbostyril ; 4-Hydroxy-1-methyl-2(1H)-quinolinone ; 4-Hydroxy-1-methylcarbostyril ; N-Methyl-4-hydroxykarbostyril ; 2(1H)-Quinolinone, 4-hydroxy-1-methyl- ; Carbostyril, 4-hydroxy-1-methyl-
Product Categories: Intermediates of Dyes and Pigments;Building Blocks;Heterocyclic Building Blocks;Quinolines
CAS NO: 1677-46-9
Molecular Formula: C₁₀H₉NO₂
Molecular Weight : 175.184
Molecular Structure:
EINECS:216-830-3
H bond acceptors: 3
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 40.54Å²
Index of Refraction: 1.647
Molar Refractivity: 48.022 cm³
Molar Volume: 132.088 cm³
Surface Tension: 58.289 dyne/cm
Density: 1.326 g/cm³
Flash Point: 133.756 °C
Enthalpy of Vaporization: 56.752 kJ/mol
Boiling Point: 297.555 °C at 760 mmHg
Vapour Pressure: 0.001 mmHg at 25°C
Melting Point: 269-271 °C(lit.)

4-Hydroxy-1-methyl-2(1H)-quinolone Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	180mg/kg (180mg/kg)		U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#01354,

4-Hydroxy-1-methyl-2(1H)-quinolone Consensus Reports

Reported in EPA TSCA Inventory.

4-Hydroxy-1-methyl-2(1H)-quinolone Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38: 4-Hydroxy-1-methyl-2(1H)-quinolone (CAS NO.1677-46-9) is irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: FG7350000
Hazard Note: Irritant

Poison by intravenous route.4-Hydroxy-1-methyl-2(1H)-quinolone (CAS NO.1677-46-9) is mildly toxic by ingestion. An eye irritant. When heated to decomposition it emits toxic fumes of NO_x.

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