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Name	ACETOHEXAMIDE	EINECS	N/A
CAS No.	968-81-0	Density	1.3g/cm3
PSA	100.72000	LogP	4.07240
Solubility	0.25g/L(25 oC)	Melting Point	188-190° (GB 912789); mp 175-177° (Marshall)
Formula	C15H20 N2 O4 S	Boiling Point	N/A
Molecular Weight	324.401	Flash Point	N/A
Transport Information	N/A	Appearance	N/A
Safety	Human reproductive effects by an unspecified route: stillbirth. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of SO_x and NO_x.	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	Urea,1-[(p-acetylphenyl)sulfonyl]-3-cyclohexyl- (6CI,8CI);1-(p-Acetylbenzenesulfonyl)-3-cyclohexylurea;1-[(p-Acetylphenyl)sulfonyl]-3-cyclohexylurea; Acetohexamid; Acetohexamide;Dimelin; Dimelin (antidiabetic); Dimelor; Dymelor; Gamadiabet; Hypoglicil;Metaglucina; Minoral; N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea; Ordimel;Tsiklamid; U 14812

ACETOHEXAMIDE Chemical Properties

Product Name: Acetohexamide (CAS NO.968-81-0)

Molecular Formula: C₁₅H₂₀N₂O₄S
Molecular Weight: 324.4g/mol
Mol File: 968-81-0.mol
Einecs: 213-530-4
Appearance: White fluffy crystalline powder with almost no odor
Density: 1.3 g/cm³
Solubility: DMSO: 45 mg/mL
Surface Tension: 55.7 dyne/cm
XLogP3: 2.4
H-Bond Donor: 2
H-Bond Acceptor: 4

ACETOHEXAMIDE Uses

Acetohexamide (CAS NO.968-81-0) is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2, particularly in people whose diabetes cannot be controlled by diet alone.It lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. For this reason, acetohexamide is not used to treat diabetes mellitus type 1.

ACETOHEXAMIDE Production

First be obtained on the amino-acetyl-benzene-acetyl benzene sulfonamide, and then continue to work with cyclohexyl isocyanate reaction of vinegar and sulfur ring has been urea

ACETOHEXAMIDE Toxicity Data With Reference

1.		unr-wmn TDLo:900 mg/kg (26-39W preg):REP		BMJOAE British Medical Journal. 2 (1964),187.
2.		orl-rat LD50:5000 mg/kg		TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185.

ACETOHEXAMIDE Consensus Reports

NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-50 ,1978. . Reported in EPA TSCA Inventory.

ACETOHEXAMIDE Safety Profile

Human reproductive effects by an unspecified route: stillbirth. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of SO_x and NO_x.
Safety Information of Acetohexamide (CAS NO.968-81-0):
Safety Statements: 36
36: Wear suitable protective clothing

ACETOHEXAMIDE Specification

Acetohexamide ,its CAS NO. is 968-81-0,the synonyms is 4-Acetyl-n-[(cyclohexylamino)-carbonyl]benzenesulfonamide ; Acetohexamide ; 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexyl-ure ; 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea ; 1-(p-Acetylbenzenesulfonyl)-3-cyclohexylurea ; 4-Acetyl-n-((cyclohexylamino)carbonyl)-benzenesulfonamid ; 4-Acetyl-n-[(cyclohexylamino)carbonyl]-benzenesulfonamid ; 4-Acetyl-n-benzenesulfonamide .

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