Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

APHOLATE
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

APHOLATE

 EINECS N/A
CAS No. 52-46-0 Density 2.32g/cm3
PSA 84.57000 LogP -0.33360
Solubility 100g/L(temperature not stated) Melting Point 147.5°
Formula C12H24 N9 P3 Boiling Point °Cat760mmHg
Molecular Weight 387.304 Flash Point °C
Transport Information N/A Appearance N/A
Safety Poison by ingestion and intramuscular routes. An experimental teratogen. Other experimental reproductive effects. Human mutagenic data. Questionable carcinogen. When heated to decomposition it emits very toxic fumes of NOx and POx. Risk Codes N/A
Molecular Structure Molecular Structure of 52-46-0 (2,2,4,4,6,6-hexaaziridin-1-yl-1,3,5-triaza-2$l^{5},4$l^{5},6$l^{5}-tri phosphacyclohexa-1,3,5-triene) Hazard Symbols N/A
Synonyms

1,3,5,2,4,6-Triazatriphosphorine,2,2,4,4,6,6-hexakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro- (6CI,7CI,8CI,9CI);2,2,4,4,6,6-Hexahydro-2,2,4,4,6,6-hexakis(1-aziridinyl)-1,3,5,2,4,6-triazatriphosphorine;2,2,4,4,6,6-Hexakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro-1,3,5,2,4,6-triazatriphosphorine;2,2,4,4,6,6-Hexakis(1-aziridinyl)cyclotriphosphaza-1,3,5-triene; APN; Apholate;ENT 26316; Hexa(1-aziridinyl)triphosphatriazine;Hexakis(aziridinyl)phosphotriazine; Myko 63; NSC 26812

Article Data 4

APHOLATE Chemical Properties

Product Name: Apholate (CAS NO.52-46-0)


Molecular Formula: C12H24N9P3
Molecular Weight: 387.3005 g/mol
Mol File: 52-46-0.mol
Density: 2.32 g/cm3
Surface Tension: 186.5 dyne/cm
XLogP3-AA: 0.6
H-Bond Donor: 0
H-Bond Acceptor: 9

APHOLATE Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - domestic LD50 oral 179mg/kg (179mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: ATAXIA		 Toxicology and Applied Pharmacology. Vol. 9, Pg. 279, 1966.
bird - wild LD50 oral 246mg/kg (246mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: ATAXIA		 Toxicology and Applied Pharmacology. Vol. 9, Pg. 279, 1966.
chicken LD50 oral 246mg/kg (246mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: ATAXIA		 Toxicology and Applied Pharmacology. Vol. 9, Pg. 279, 1966.
domestic animals - goat/sheep LDLo intramuscular 5mg/kg (5mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Annals of the New York Academy of Sciences. Vol. 111, Pg. 715, 1964.
domestic animals - goat/sheep LDLo oral 50mg/kg (50mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 Annals of the New York Academy of Sciences. Vol. 111, Pg. 715, 1964.
mouse LD50 intraperitoneal 50mg/kg (50mg/kg)   Journal of Medicinal Chemistry. Vol. 29, Pg. 1341, 1986.
mouse LD50 oral 110mg/kg (110mg/kg)   Journal of Agricultural and Food Chemistry. Vol. 14, Pg. 301, 1966.
mouse LD50 subcutaneous 25mg/kg (25mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"

BLOOD: CHANGES IN SPLEEN

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"		 Farmakologiya i Toksikologiya Vol. 8, Pg. 73, 1973.
quail LD50 oral 179mg/kg (179mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: ATAXIA

BEHAVIORAL: FOOD INTAKE (ANIMAL)		 Toxicology and Applied Pharmacology. Vol. 9, Pg. 279, 1966.
rabbit LD50 intravenous 2900ug/kg (2.9mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

BLOOD: CHANGES IN SPLEEN		 Farmakologiya i Toksikologiya Vol. 8, Pg. 73, 1973.
rat LD50 oral 98mg/kg (98mg/kg)   Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969.
rat LD50 skin 400mg/kg (400mg/kg)   Bulletin of the World Health Organization. Vol. 31, Pg. 737, 1964.
rat LD50 subcutaneous 21mg/kg (21mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

BLOOD: CHANGES IN SPLEEN		 Farmakologiya i Toksikologiya Vol. 8, Pg. 73, 1973.

APHOLATE Consensus Reports

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 9 (1975),p. 31.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

APHOLATE Safety Profile

Poison by ingestion and intramuscular routes. An experimental teratogen. Other experimental reproductive effects. Human mutagenic data. Questionable carcinogen. When heated to decomposition it emits very toxic fumes of NOx and POx.

APHOLATE Specification

 Apholate ,its CAS NO. is 52-46-0,the synonyms is 2,2,4,4,6,6-Hexaaziridin-1-yl-1,3,5-triaza-2$l^{5},4$l^{5},6$l^{5}-tri phosphacyclohexa-1,3,5-triene ; 2,2,4,4,6,6-Hexakis(1-aziridinyl)-2,2,4,4,6,6-hexahydro-1,. ; Apn ; Myko 63 ; Myko-63 ; Nsc-26812 ; Om-2174 .

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 52-46-0